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Biomedical subjects

M Sunakawa

Publications and source records attributed to M Sunakawa.

At least 37 records · Page 2Linked to original sources
PubMed1988

Elevation of tissue PO2 with improvement of tissue perfusion by topically applied CO2.

Local absorption of CO2 was examined, by tissue gas analysis with medical mass spectrometry, in rabbits placed in a bath. The results obtained clearly showed that (1) Elevation of subcutaneous tissue PO2 was followed by elevation of PCO2 in the subcutaneous tissue. (2) Local absorption of CO2 through skin was confirmed by elevation of the levels of subcutaneous PO2 and PCO2 at the site exposed to CO2. (3) Tissue perfusion during the CO2 bath was moderately higher than that observed with tap water bathing. The mechanism of oxygen release into the tissue by CO2 bathing is thought to involve increased [H+] and PCO2 in the red blood cells, which shifts the hemoglobin dissociation curve to the right, thus facilitating oxygen release at the tissue level. There is, therefore a good possibility, that the improved tissue perfusion together with the increased oxygen in the tissue will favourably affect wound healing and chronic degenerative disorders, thus facilitating rehabilitation.

Animals↗
PubMed1988

Fibrinopeptide A and fibrinopeptide B beta 15-42 in patients with Behçet's disease.

Plasma levels of FPA and FPB beta 15-42 in patients with Behçet's disease were examined. In the patients, the mean levels of FPA and FPB beta 15-42 were significantly higher than controls (p less than 0.001). Fibrinolysis subsequent to coagulation may be activated in the patients. The levels of both FPA and FPB beta 15-42 were higher during attack than in remission. The caution should be taken these levels to understand the disease activity.

Behcet Syndrome↗
PubMed1985

Epstein-Barr virus-related antibody pattern in uveitis.

Epstein-Barr virus-related antibody titers were determined in 30 patients with anterior uveitis, 45 with pan-uveitis, including 19 with Behçet's disease, 11 with Vogt-Koyanagi-Harada's disease and 15 with unclassified pan-uveitis, and 144 age-matched healthy controls. The frequencies of anti-VCA (viro-capsid antigen) and anti-EA (early antigen) in uveitis patients and in controls were similar, but the frequency of sera with elevated titers (greater than or equal to 1:160) and the geometric mean titer of anti-VCA in the patients with anterior uveitis was significantly higher than in the controls (P less than 0.025, P less than 0.01) and in the patients with pan-uveitis (P less than 0.001). The frequency of sera with elevated titers of anti-EBNA (Epstein-Barr virus associated nuclear antigen) (greater than or equal to 1:160) in the patients with pan-uveitis was significantly lower than in the controls (P less than 0.02) and in the patients with anterior uveitis (P less than 0.01). Among the patients with pan-uveitis, there was no significant difference in the pattern of antibodies. These data are compatible with the interpretation that there may be both anatomical and immunological differences between anterior and pan-uveitis.

Antibodies, Anti-Idiotypic↗