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Biomedical subjects

M Suwo

Publications and source records attributed to M Suwo.

14 recordsLinked to original sources
PubMed1994

[A study of biological characteristics of large bowel adenocarcinomas showing mucin production; examination of histological differentiation and cell kinetics].

In order to clarify the biological behavior of mucin producing cancers of colon, we analyzed 32 cases showing histological heterogeneity in the tumors, by mucin histochemistry. 28 cases were mucinous adenocarcinoma, forming with tubular structures, and the remaining 4 cases were signet-ring cell carcinomas. HID-AB stain demonstrated that the mucin component was almost similar to that of normal mucosa around the cancer. In the tubular forming portions, in which polyploid or aneuploid cells were often detected, the growth fraction of cancers was significantly higher than in that of the other portions.

Adenocarcinoma, Mucinous↗
PubMed1989

[A case of mediastinal neurilemmoma diagnosed by X-ray guided needle biopsy].

A 70-year-old female was admitted to our hospital complaining of general lassitude. She had been treated for duodenal ulcer. A routine chest X-ray film at admission showed a large tumorous shadow in the right apical field. A computed tomographic scan revealed that it was a posterior mediastinal tumor containing multiple cystic lesions. After medical treatment for duodenal ulcer, a needle biopsy was performed for histological diagnosis. Under local anesthesia a small skin incision was made in the supraclavicular region to avoid parietal pleura and great vessels and a specimen was obtained by a needle guided by X-ray fluoroscopy. The tumor was diagnosed as neurilemmoma histologically. She was discharged because the complaint subsided. Five months later, however, she was again admitted complaining of righ nuchal pain. Thoracotomy was performed under general anesthesia and the tumor growing from the second intercostal nerve was resected. It was 5 x 4 x 5.5 cm in size, encapsulated and consisted of multiple cystic lesions macroscopically. It was confirmed as Antoni B type neurilemmoma histologically. The nuchal pain subsided and she has been doing well for more than three years after discharge. Recently computed tomography (CT) and ultrasonography (US) have been widely used as a guiding device for needle biopsy. In this case, however, CT guided needle biopsy was not applied for fear of possible complications such as pneumothorax. It was also impossible to perform US guided needle biopsy because the tumor was behind the costal and sternal bones and could not be visualized.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗
PubMed1986

[Right and left coronary arteries-right atrial fistulas diagnosed by Doppler echocardiography: a case report].

An interesting case of right and left coronary arteries-right atrial fistulas diagnosed by Doppler echocardiography was presented. A 59-year-old woman was referred for evaluation of her continuous murmur. A thrill was palpable at the left sternal border in the third intercostal space. The proximal portions of the dilated right and left coronary arteries and distal portions of the tortuous and converging fistulas of both coronary arteries were imaged by two-dimensional echocardiography. Bidirectional continuous turbulent Doppler signals were detected in the proximal portions of the dilated right and left coronary arteries, in the distal portions of the fistulas around the crux and in the right atrium. These findings facilitated our diagnosis of right and left coronary arteries-right atrial fistulas. The flow velocity at the ostium of the right coronary artery was highest and nearly the same as the flow velocity (about 2 m/s) obtained by continuous wave Doppler from the maximum point of the thrill. The maximum pressure difference was considered located at this portion. Selective coronary angiography confirmed the right coronary artery and left main trunk-left circumflex coronary artery to be large, elongated and tortuous. These fistulas were communicating with the right atrium. This case demonstrates the usefulness of Doppler echocardiography in the noninvasive diagnosis of coronary arteriovenous fistula.

Arteriovenous Malformations↗
PubMed1983

[Two-dimensional echo-cardiographic study on left atrial thrombi in patients with a mitral prosthetic valve].

Two-dimensional echocardiographic study was performed to detect left atrial thrombi in 33 patients with a prosthetic mitral valve. The subjects were 9 males and 24 females and their ages ranged from 21 to 61 years (average 43.2 years). Their prosthetic valves consisted of 18 Hancock, three Carpentier-Edwards, four Björk-Shiley, four Starr-Edwards and four St. Jude Medical valves. Two-dimensional echocardiograms were obtained using a Toshiba SSH-11A echograph with an electronic phased-array scanner. The left parasternal, apical, subcostal and right parasternal windows were used to detect left atrial thrombi. In five of the 33 patients, a left atrial thrombus was demonstrated as a mass echo attached to the posterior wall of the left atrium. The clinical and echographic features of five patients with a left atrial thrombus (Group A) were compared to those of 28 patients without it (Group B). The average age at the time of operation was 44.6 +/- 9.7 years in Group A and 43.0 +/- 9.5 years in Group B, showing no difference between the two groups. In 10 of the 33 patients, a left atrial thrombus was confirmed by the initial operation. In only one of these 10 patients, a left atrial thrombus was demonstrated by post-operative two-dimensional echocardiographic examination. The presence or absence of a left atrial thrombus in the pre-operative stage did not clearly relate to the occurrence of a left atrial thrombus in the post-operative stage. The cardio-thoracic ratio was significantly greater (p less than 0.01) in Group A (74.4 +/- 6.3%) than in Group B (58.1 +/- 8.1%). Left atrial dimension by M-mode echocardiograms was significantly greater (p less than 0.05) in Group A (70.6 +/- 11.3 mm) than in Group B (51.6 +/- 7.7 mm). The length of the pseudo-septalized left ventricular posterior wall was longer (p less than 0.05) in Group A (34.0 +/- 11.5 mm) than in Group B (12.8 +/- 9.4 mm). The angle between the perpendicular to the mitral annulus and the upper part of the interventricular septum was significantly greater (p less than 0.01) in Group A (58.6 +/- 18.0 degrees) than in Group B (18.8 +/- 9.6 degrees). The characteristics observed in Group A were thought to be caused mainly by the giant left atrium. Therefore it is concluded that there is a close relationship between left atrial thrombi and the giant left atrium in patients with a mitral prosthetic valve.

Adult↗
PubMed1982

[Evaluation of left ventricular diastolic chamber stiffness by the apexcardiogram and echocardiogram].

This study was made to evaluate left ventricular (LV) chamber stiffness noninvasively utilizing the apexcardiogram and echocardiogram. Subjects were 13 patients with left ventricular hypertrophy (LVH) and 17 patients without LVH. Cardiac catheterization and LV angiography were also performed in all patients. In the apexcardiogram, as shown in Figs. 1 and 2, the ratios of an amplitude to the total amplitude were measured at the onset of left atrial systole (H1) (80 msec after the onset of the P wave) and the peak of A wave (H2). In the echocardiogram, LV internal diameters were determined at 80 msec after the onset of the P wave (D1) and the peak of the R wave of ECG (D2). In addition left ventricular volumes, V1 and V2, were calculated by D1 and D2 using Teichholz's method. Increments of the ratio of an amplitude of the ACG wave (delta H = H2-H1) and LV volume changes (delta V = V2-V1) which are associated with left atrial systole were calculated. The ratio of delta H to delta V (delta H/delta V) was defined as a measure of LV diastolic chamber stiffness. On the other hand, various parameters (delta P/delta V, K, dV/dP, dV/VdP) which represent LV diastolic properties were determined by LV pressure curves and LV cineangiograms. delta H/delta V by noninvasive method showed good correlations with delta P/delta V (r = 0.83), K (r = 0.68), dV/dP (r = -0.80) and dV/VdP (r = -0.75), respectively. The correlations were much better between delta H/delta V and these parameters than between A/Eo and these parameters. Patients with LVH had much greater diastolic stiffness (delta H/delta V = 2.03 +/- 1.10) than those without LVH (delta H/delta V = 0.60 +/- 0.29, p less than 0.01). It is concluded that delta H/delta V obtained from ACG and the echocardiogram is a useful parameter to evaluate LV diastolic chamber stiffness noninvasively and this ratio is well correlated with LVH.

Adolescent↗