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Biomedical subjects

M Szmidt

Publications and source records attributed to M Szmidt.

At least 73 records · Page 4Linked to original sources

Catamenial pneumothorax.

A report is given of a 46-year-old woman, who had nine recurrencies of a catamenial right-sided pneumothorax. During anovulatory hormone treatment no recurrency was noted for the following 6 months.

Chlormadinone Acetate↗

[Need to consider various factors predisposing to chronic nonspecific lung diseases in pre-employment orientation. Current state of the studies and research].

The authors raise the problem of the factors predisposing to chronic nonspecific pulmonary diseases and the need to consider them in contemporary prophylaxis, especially in preemployment orientation. What is most important is bronchial hyperreactivity, accompanied by atopy or not, in the pathogenesis of asthma and spastic bronchitis, as well as disturbances of proteinases (elastase)--their inhibitors (alpha-1-antitrypsin) system in early emphysema pathogenesis.

Acetylcholine↗

Aspirin-induced urticaria--a clinical study.

This paper describes the clinical characteristics of patients with aspirin-induced urticaria. The group of 71 patients (49 women and 22 men), with a mean duration of symptoms of 32.5 years, underwent allergological, laryngological and histamine dihydrochloride inhalation tests. Nasal polyps were found in 2 patients (2.8%), atopic disease in 23 (32.3%) and at least one feature of atopy in 37 (51.9%). Forty-nine patients (69%) suffered from urticaria which was not associated with aspirin. In 22 patients, urticaria developed solely due to aspirin. Urticaria not associated with aspirin has been present from 2 weeks to 30 years before the onset of sensitivity to aspirin. The authors conclude that aspirin-induced urticaria results from two different concomitant phenomena, i.e. sensitivity to aspirin and urticaria not associated with ingestion of the drug.

Adolescent↗

Urticaria/angioedema-type sensitivity to aspirin and other nonsteroidal anti-inflammatory drugs. Diagnostic value of anamnesis and challenge test with acetylsalicylic acid.

The aim of this study was to determine the value of challenge tests with acetylsalicylic acid in the diagnosis of ASA-induced urticaria. The study was performed in 71 patients with suspected urticaria/angioedema-type sensitivity to ASA. Anamnesis confirmed sensitivity in 67 patients (94.4%) and showed that sensitive patients usually suffered from extensive urticaria (37 patients, i.e 55.5%) after ingestion of ASA. Eight patients (12%) reacted with loss of consciousness and 4 (6.0%) with edema of the larynx. Oral challenge test with acetylsalicylic acid was performed in 53 patients, in 49 (92.4%) of whom it was positive. Threshold doses of acetylsalicylic acid ranged from 40 to 300 mg. In 11 patients, the test was repeated and in 8 it was performed 3 times. It was observed that both the threshold acetylsalicylic acid doses and the time of appearance of sensitivity symptoms were variable. All ASA-sensitive patients reacted to indomethacin in a similar manner as to ASA. Paracetamol, on the other hand, was well tolerated by all 25 evaluated patients with urticaria/angioedema-type sensitivity to ASA.

Acetaminophen↗