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Biomedical subjects

M T Baixench

Publications and source records attributed to M T Baixench.

11 recordsLinked to original sources

Clinical and experimental evaluation of a new chromogenic medium (OCCA, Oxoid) for direct identification of Candida albicans, C. tropicalis and C. krusei.

Oxoid Chromogenic Candida Agar (OCCA) is a new commercial ready-to-use medium that contains chromogenic substrates for rapid detection and specific identification of Candida albicans, C. tropicalis and C. krusei. We evaluated the performance of this medium with 364 clinical specimens and 31 subcultures, and examined its ability to support the growth of small inocula of six reference strains. CHROMagar Candida was used as the reference medium. OCCA permitted the growth of most important yeasts, and readily discriminated among Candida spp. in clinical specimens, including mixed cultures.

Candida↗

Localized oral Fusarium infection in an AIDS patient with malignant lymphoma.

We report here a case of localized oral Fusarium infection in an AIDS patient who developed an ulceration in the soft palate. Fusarium solani was identified by histopathology and culture. We believe this to be the second reported case of oral Fusarium infection in a patient with haematological malignancy and the first reported association of oral Fusarium infection with AIDS.

AIDS-Related Opportunistic Infections↗

[Two cases of inexplicable autochthonous malaria in Toulouse, France].

Malaria involving both Plasmodium falciparum and vivax was observed in two patients hospitalized in the same room of the Cardiology Department of the Purpan University Hospital in Toulouse, France. One patient was in coma without fever by the time of diagnosis. None of the patients had traveled to malaria areas within the last 33 years. Epidemiological investigations failed to detect malaria in family members, hospital staff, or other patients. Transmission due to transfusion of infected blood, use of contaminated surgical instrumentation, or bite of an autochthonous anopheles mosquito was reasonable ruled out. Since Toulouse International Airport is located less than three kilometers from the Purpan University Hospital, the most likely explanation was airport-acquired malaria due to the bite of a mosquito imported by an aircraft coming from abroad. The hypothesis that an Anopheles mosquito survived the plane trip and then was blown into the patients' room was supported by temperature and wind conditions prevailing at the time of infection.

Aged↗

[Fusarium onychomycosis].

INTRODUCTION: A 69-year-old man with an uneventful past history consulted for a proximal subungueal leukonychia and associated paronychia of the right greater toe. Macroscopic examination and culture lead to the diagnosis of Fusarium oxysporum. Local treatment with bifonazol and cyclopirox was effective. DISCUSSION: Fungal onychomycoses are uncommon and usually present as superficial leukonychia. The association of a proximal localization with paronychia would suggest possible Fusarium infection. Though no specific treatment protocol is well-established, this case emphasizes the importance of effective treatment since invasive fusariosis is described in immunosuppressed patients with ungueal localizations can be an important portal for infection.

Aged↗

[Seroepidemiology of toxoplasmosis in Niamey, Niger].

A seroepidemiological survey of toxoplasmosis was carried out in Niamey, Niger, in 1992. Three hundred and seventy-one sera from 200 females and 171 males were tested by indirect immunofluorescence assay for IgG. Using a cut-off value of 12 UI, 67 sera (18%) were positive. In this group detection of specific IgM by ELISA with immunocapture revealed 8 positive sera (11.9%). Seroprevalence of specific IgG was not correlated with ethnic origin or sex but did increase with age from 6.9% in subjects under 5 years to 34.9% in subjects 50 years and over. These findings are comparable with those from previous studies in similar climates and confirm that the prevalence of toxoplasmosis is higher in humid coastal regions than dry desert areas.

Adolescent↗

[Seroepidemiology of toxoplasmosis on Mayotte (Comores Archipelago)].

A seroepidemiological survey of toxoplasmosis was carried out on Mayotte Island. Detection of IgG was performed on 871 samples from 509 females and 362 males by indirect immunofluorescence assay. Using a cut-off value of 12 UI (1/16), 734 sera (84.3%) were found to be positive. Assays for specific IgM which were carried out only in positive subjects detected IgM in 13 people (1.5%). Comparison between different ethnic groups showed significantly higher rates of seroprevalence in villages with latrines. This finding is attributed to the use of fresh water for bathing and dish washing. It has been hypothesized that use of salt water for these purposes lessens the rate of contamination by destroying Toxoplasma gondii oocysts.

Adolescent↗

[Delayed testing for the diagnosis of fungi in the urines. Evaluation of the BD Vacutainer C&S tubes for the storage of urine samples at room temperature].

The study included 37 urine samples which have been artificially infected with low levels (10(3) CFU/mL) of various fungi strains. We compared the effects of sample storage, up to 48 hours, at room temperature, in a urine evacuated tube containing specific additives with storage at + 4 degrees C, for the same length of time, in a urine evacuated tube without any additives. There have been no differences of results (speed of growth and colony size) between the 2 modes of storage. However, the experience has shown that samples needed a careful mixing before seeding to avoid underdetection of the strains. Based on the study results, the BD Vacutainer C&S tubes are suitable for delayed testing for the diagnosis of urine fungal infection.

Equipment Design↗