[Precision chromatographic-mass spectrometric analysis of urinary composition].
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Biomedical subjects
Publications and source records attributed to M T Dmitriev.
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Conditions for extraction, desorption and concentration of specific substances, such as metabolites, and characteristics of their gas-chromatographic division and mass-spectrometric identification have been established. A library for mass-spectra of specific metabolite compounds characteristic of various diseases has been set up. Computer programs for metabolite analysis and for diagnosis were modified. An experimental introduction of chromatographic-mass-spectrometric diagnosis into practice in a number of hospitals and research institutions for prophylactic medical examination of people will make it possible to quickly accumulate statistic data and create the necessary data bank.
It is for the first time that chromato-mass-spectrometry has been used to examine human wastes. The data on the excretion rate of specific organic compounds can be employed to predict the content of toxic metabolites in the enclosed environment, to give their biomedical characterization, and to diagnose unfavorable changes in the body.
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