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Biomedical subjects

M T Erickson

Publications and source records attributed to M T Erickson.

At least 19 recordsLinked to original sources

The application of structural equation modeling to maternal ratings of twins' behavioral and emotional problems.

The application of structural equation modeling to twin data is used to assess the impact of genetic and environmental factors on children's behavioral and emotional functioning. The models are applied to the maternal ratings of behavior of a subsample of 515 monozygotic and 749 dizygotic juvenile twin pairs, ages 8 through 16, obtained through mailed questionnaires as part of the Medical College of Virginia Adolescent Behavioral Development Twin Project. The importance of genetic, shared, and specific environmental factors for explaining variation is reported for both externalizing and internalizing behaviors, as well as significant differences in the causes of variation in externalizing behaviors among young boys and girls. The usefulness of applying structural equation models to data on monozygotic and dizygotic twins and the potential implications for addressing clinically relevant questions regarding the causes of psychopathology are discussed.

Adolescent

Concurrent validity of the Minnesota Child Development Inventory with high-risk infants.

Investigated the validity and clinical utility of the Minnesota Child Development Inventory (MCDI) as a developmental screening instrument with a sample of 280 premature infants identified as medically and socioeconomically high risk for developmental delays. Correlational analyses demonstrated significant correlations between the MCDI scales and the criterion Bayley Mental Age Equivalent score. Results of a moderator multiple regression analysis indicated that parent and child characteristics have a statistically significant "moderating" influence on the validity of the MCDI although the clinical significance of this finding may be minimal. A prediction-performance matrix analysis revealed a high degree of classification specificity (92%) but a relatively low sensitivity rating (56%). Findings suggest that the MCDI is a valid and useful screening instrument for high-risk infants but should be used diagnostically only in conjunction with other measures.

Adolescent

Rethinking Oedipus: an evolutionary perspective of incest avoidance.

The author presents a biological hypothesis of incest avoidance. Pertinent literature from evolutionary biology, ethology, anthropology, and clinical research is reviewed. Secure early bonding to immediate kin predicts later adaptive kin-directed behaviors, including preferential altruism (kin selection) and incest avoidance. Impaired bonding predicts aberrant kin-directed behavior, including diminished altruism, neglect, and an increased incidence of incest. Failed bonding predicts the highest frequency of incest. Secure bonding to kin may function to establish adaptive kin-directed behaviors, including incest avoidance. Bonding is conceived of as the developmental foundation of a form of social attraction, here called "familial attraction," which is evolutionarily distinct from sexual attraction.

Altruism

Childhood behavior problems: a comparison of twin and non-twin samples.

This study compares standardized measures of childhood behavior problems in a community-based twin sample with those for normative samples from the general population. Maternal parent ratings on the Child Behavior Checklist (CBCL) for 1824 twins were compared with the CBCL normative sample. The results indicated that twins showed small but consistently higher levels of problem behaviors. These elevations were significant for older children on both internalizing and externalizing behaviors; for younger children the elevations were significant for externalizing but not internalizing behaviors.

Adolescent

Children's self-statements and adjustment to elective outpatient surgery.

Children's coping self-statements, levels of anxiety, degree of behavioral adjustment, as well as levels of maternal state anxiety and parenting style, and demographic variables were used to predict the reactions of 61 children to elective day surgery. Results indicated that elective day surgery was not psychologically traumatic for most children. However, the use of negative self-statements and both low and high maternal anxiety were found to be related to increased anxiety of the children experiencing elective day surgery.

Adaptation, Psychological

Early life events as discriminators of socialized and undersocialized delinquents.

The relationship between early life events and the socialized and undersocialized dimensions of conduct disorder was investigated. Subjects were 40 incarcerated male delinquents and their mothers. The mothers were administered the Children's Life Events Questionnaire and the Developmental Questionnaire. Youths were administered the Adolescent Parent Relations Scale. The results indicated that the undersocialized delinquents had a greater number of stressful life events during their first 4 years of life than did the socialized delinquents. Discriminant function analysis indicated that stressful life events during the 2nd and 4th years were the most important predictors of membership in the undersocialized group. The discriminant function generated was able to classify 82.5% of the sample correctly. The remaining variables did not significantly discriminate the groups.

Adolescent

Differential expression of pseudoconditioning and sensitization by siphon responses in Aplysia: novel response selection after training.

Nonassociative training with a noxious unconditioned stimulus (US) applied to the head or tail of freely moving Aplysia caused a qualitative change in siphon responses to midbody test stimulation, so that the midbody test responses came to resemble the unconditioned siphon response (UR) to the US when tested 1 d after exposure to the US. Such a nonassociative, US-induced transformation of test responses into responses resembling the UR has traditionally been termed "pseudoconditioning." Short-term pseudoconditioning was compared to sensitization and to habituation in a reduced preparation that used a photocell to distinguish "head-type" siphon responses from qualitatively different "tail-type" responses. Transformation of test responses (pseudoconditioning) was observed only when the type of preexisting alpha response to the midbody test stimulus was different from the UR. Sensitization, defined as a US-induced enhancement of the alpha response to the test stimulus, was observed when the initial alpha response and the UR were of the same type. General sensory facilitation was excluded as a critical mechanism for pseudoconditioning by the observation that the same midbody test response could be transformed to either a head-type or tail-type response, depending on the site of the US, and by the observation that simply increasing the intensity of the midbody test stimulus in the absence of a head or tail US did not produce similar response transformations. These studies demonstrate pseudoconditioning in a preparation amenable to analysis at the level of identified neurons, and draw attention to a distinctive and widespread form of behavioral modifiability that has been neglected by investigators of learning.

Animals

Directional control and the functional organization of defensive responses in Aplysia.

Noxious cutaneous stimulation of anterior sites on Aplysia californica causes withdrawal and turning followed by escape locomotion. Stimulation of anterior sites causes significantly larger turning responses than does stimulation of posterior sites, so that escape locomotion is always directed away from a site of 'attack'. Later phases of escape locomotion are often the same, regardless of the site of the triggering stimulus. The defensive secretions, ink and opaline, are directed along the anterior-posterior axis at the source of noxious stimulation. Ink and opaline ejections are directed to the front or back of the animal by characteristic responses of the siphon, mantle, and parapodia. Ink and opaline are ejected by a series of coordinated pumping movements of the mantle, gill, and parapodia that closely resemble triggered 'respiratory pumping' or 'Interneuron II' episodes (Kupfermann and Kandel 1969; Byrne and Koester 1978; Hening 1982). The directed ejection of secretions from the mantle cavity in response to noxious stimulation suggests a number of potential defensive functions for these secretions including aggressive retaliation, startle display, diversion, and alarm signalling (Edmunds 1975). Taken together, our results and others' suggest an integrated scheme for the functional organization of overt defensive behavior in Aplysia, and begin to suggest testable hypotheses about the integration of defensive responses on the cellular level in this animal.

Animals

The Child Abuse Potential Inventory: a study of concurrent validity.

Forty-four subjects were assigned to a High or Low Abuse Potential Group based upon their Child Abuse Potential (CAP) Inventory's abuse scale scores. Each subject's heart rate (HR) and skin conductance (SC) were monitored while the subject was viewing videotape presentations of an infant smiling, crying, or quiescent. The High Abuse Potential Group had a faster peak HR throughout the videotape presentations with no significant differences among videotape segments. The Low Abuse Potential Group had a slower peak HR and had a significantly lower HR during the Smile and Cry segments than in the second Quiescent segment. The males accounted for most of the significant SC variability among tape segments. The pattern of SC responses revealed that the males were less aroused than the females, the Low Abuse Potential Group was less aroused than the High Abuse Potential group, and all four groups showed a decrease in arousal toward the end of the videotape presentations. The results provide support for the concurrent validity of the CAP inventory.

Arousal

The psychological, social, and medical needs of lower socioeconomic status mothers of asthmatic children.

Extensive clinical literature describes parental reactions and stages of adjustment to chronic illnesses of their children, but such observations have not yet been empirically demonstrated. Utilizing a cross-sectional approach, the present study examined the psychological/emotional, social/instrumental, and medical/educational problems experienced by lower socioeconomic status (SES) mothers of 45 asthmatic children as a function of the length of time that had elapsed since the diagnosis of their children's illness. Data analysis indicated that the problem areas did not vary with the length of time since diagnosis. The majority of mothers reported difficulties related to their children's illness in each area.

Adaptation, Psychological

Effects of grade, gender, and hospitalization on children's medical fears.

First, fourth, and seventh graders completed a specially designed medical fears questionnaire. The effects of grade, gender, and previous hospitalization on the children's medical fears were analyzed. Gender was found to be significantly related to both the frequency and intensity of medical fears, with girls expressing more and stronger fears than boys. Fourth and seventh graders reported more medical fears than first graders. Previous hospitalization experience had no effect on the frequency or intensity of medical fears.

Adolescent

WISC characteristics of reading disabled children identified by three objective methods.

The WISC and Spache Reading Diagnostic Scales were administered to 119 third-grade children. Groups of reading disabled children were selected by three objective methods (Below Grade Level, Bond and Tinker, and the Erickson Z-score Discrepancy). The Below Grade Level and Bond and Tinker methods tended to identify the same children whose IQs and reading achievement scores were below average. The Z-score method identified children with IQs at or above the group average. Comparison of the poor readers with control groups matched for IQ and sex gave only minimal evidence for WISC subtest patterns as characteristic of poor readers.

Achievement

Bias against genetic hypotheses in adoption studies.

Genetic factors are implicated in the cause of psychopathological disorders whenever the incidence of disorder is greater among the adopted-away offspring of affected parents than among those of control (unaffected) parents. The lack of information about most parents who give their children up for adoption could result in the inclusion of a substantial number of high-risk parents in the control groups. This could bias an adoption study against a genetic hypothesis. The Minnesota Multiphasic Personality inventory scores of two groups of pregnant unwed mothers were compared to those of two other groups: married pregnant women and 18-year-old women. Comparisons disclosed that the unwed mothers had significant elevations on five to the nine clinical scales. Elevations on psychopathic deviancy and schizophrenia were particularly substantial. These results indicate a requirement to select control group parents who are representative of the general population.

Adoption