Biomedical subjects
M T Schreiber
Publications and source records attributed to M T Schreiber.
Mania scale scores, signs, and symptoms in forty inpatients.
Forty inpatients receiving routine treatment for acute mania were rated for severity of psychopathology using a new Mania Rating Scale (MRS). Ratings wer obtained during the first week in hospital and 2 weeks thereafter. A wide range of scores was obtained at both ratings. There were significant decreases between ratings in the frequency of some but not all diagnostic signs and symptoms. Patients with sufficient signs and symptoms for a cross-sectional diagnosis of mania had significantly greater total MRS scores than those with fewer signs and symptoms. The range of overlap in total MRS scores between these groups was noted.
Mania ratings at discharge from hospital: a follow-up.
Seventeen patients hospitalized for acute mania were followed up 1 month after discharge. Ratings of psychopathology at discharge using a new Mania Rating Scale differentiated the 12 patients who maintained outpatient status for 1 month from the five who did not. Total scores greater than 14.0 predicted being rehospitalized or jailed. Significantly higher item ratings for speech (rate and amount), language-thought disorder, irritability, and disruptive-aggressive behavior were noted in the poorer compared to the better outcome group.
Effects of anticoagulants on acid-base and blood gas estimations.
The use of excessive amounts of heparin to anticoagulate blood samples for pH and blood gas analysis leads to erroneously low PCO2 results, whereas pH and PO2 are relatively unaffected. Derived base deficit values accordingly will be high. Dilution is seldom less than 6% but may exceed 40%, particularly when sampling fron neonates. Sodium citrate and Heller-Paul oxalate solutions were found to be suitable alternatives to heparin, whereas EDTA was not.