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M T Uzzauto

Publications and source records attributed to M T Uzzauto.

6 recordsLinked to original sources
PubMed1990

[Mottled hyperpigmentation of the fundus oculi associated with angioid streaks in pseudoxanthoma elasticum].

The Authors report mottled fundus in association with pseudoxanthoma elasticum in 8 of 9 patients. The mottled hyperpigmentation is an early uncommonly described finding, consisting of a speckled, yellowish mottling of the posterior pole temporal to the macula at ophthalmoscopic examination; this appearance, called "peau d'orange", is believed to be caused by changes in the retinal pigmented epithelium overlying a calcified and degenerating Bruch's membrane. This finding is virtually pathognomonic of pseudoxanthoma elasticum and may be present even in the first decade of the disease, prior to the appearance of the angioid streaks. The Authors emphasize the significance of the retinal finding, that may represent an incomplete genetic expression of an autosomal recessive carrier state.

Adolescent↗
PubMed1990

[Association of lichen planus and discoid lupus erythematosus. A clinical and histopathological study of 2 cases].

Two patients showing features of both lichen planus and lupus erythematosus are described: reticular whitish patches in the oral mucosa coexisting with chronic, partly atrophic LED-like skin lesions located on the face were present in both of them. The histological, histochemical and immunopathological findings allowed to diagnose a "LP-LE coexistence" more than a mixed LP-LE disease. The clinical, histological and immunological relationships between LP and LE are discussed and it is suggested that the pathogenesis of the coexistence of the two diseases could be related to a common pathophysiological pathway. It might be that LP and LE are due to a single aetiological agent (e.g. a virus) interacting with different genetic backgrounds to cause LE in some, LP in others and an intermediate disease in a small group of patients. The histopathological and immunopathological features that distinguish LP from LE are the concentration of lymphocytes in areas of keratinocyte damage, the different colloid bodies patterns and the direct IF findings. The Authors conclude that further studies should be performed on "LP-LE coexistence".

Adult↗
PubMed1990

[Pseudoxanthoma elasticum associated with endocrine disorders, renal and adrenal cystic dysplasia, sensorineural hearing loss and mental disorders].

The paper reports a case of a 24-year old woman affected by pseudoxanthoma elasticum with typical flexural skin and ocular lesions. Other rarely associated diseases were also present: simple colloid goitre with hypothyroidism, renal and suprarenal capsules and ovarian cysts, consequent dysfunction of the pituitary-adrenal axis, hirsutism, cochlear hypoacusis, frontal sinus hypoplasia, and neuropsychiatric disorders. The association with hypothyroidism, hypoacusis and neuropsychiatric disorders is fully discussed, and it is suggested that the latter might be caused by peripheral vascular damage.

Adrenal Gland Diseases↗
PubMed1989

[Twenty-nail dystrophy].

An idiopathic case of twenty-nail dystrophy observed in a 6 year old girl, is reported. Histopathological features obtained from a nail matrix biopsy specimen excluded lichen planus or other skin diseases. The various pathogenetic hypotheses are discussed.

Child↗