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Biomedical subjects

M Tacla

Publications and source records attributed to M Tacla.

23 records · Page 2Linked to original sources

[Crohn's disease of the duodenum associated with acute acalculous cholecystopathy].

Since the initial description of Crohn's disease (CD) located in the distal ileum, great number of cases has been observed, and we know that this disease can occur in any part of the digestive tube, from mouth to anus. The duodenal involvement is rare and no more than two hundred cases have been observed. A case of Crohn's disease located in the duodenum, with a severe acalculus cholecystitis, without intestinal involvement is presented. Radiological study showed a stenotic process in the first, second and third duodenal portion, later on confirmed by endoscopy. This was confirmed at surgery, when a gastrojejunostomy with truncal vagotomy, cholecystectomy, besides duodenum and liver biopsies were performed. The patient is asymptomatic four years after surgery. It is considered that bile reflux, resulting from involvement of Vater papilla by CD, is responsible factor of the biliary pathology.

Cholangiography↗

[Treatment of bile duct diseases. Dyskinesias. Chronic inflammation].

The approach to the integrated diagnosis of the patient with biliary tract diseases is reviewed as a basis for the appropriate treatment, taking into account the functional disturbances and the organic elements including malformation, inflammation, infection, gallstone and neoplasia. The role of impaired emptying of the gallbladder is emphasized. This condition may give origin to inflammation of the gallbladder is emphasized. This condition may give origin to inflammation of the gallbladder which is caused by the irritative action of concentrated bile acids as a consequence of the stagnated bile in the gallbladder with poor emptying. Other consequences of bile stagnation in the gallbladder is gallstone formation and biliary infection by bacterias. Thus, increase of gallbladder emptying and of bile production are advised in the treatment of biliary diseases. Such two effects can be obtained by the diet using adequate amounts of vegetables, oils and eggs and by drugs such as choleretics. A new choleretic drug-the cicloxilic acid-was used in 102 patients, 48 out of them with gallstone and 54 without lithiasis. The following three actions of this drug were recorded: a decrease of gastrointestinal gaseousness; a decrease of abdominal discomfort and soreness, and a mild laxative effect with stool of less consistency.

Adolescent↗

[Effect of cicloxilic acid on biliary dynamics].

This work was developed in order to estimate, with objective methods, the pharmacodynamic activities of a new choleretic and antilithogenic drug, the cicloxilic acid. It was determined the changes of daily biliary flow and bile composition in 8 patients with biliary system surgical intervention and "T" (Kehr) tube inserted. The cicloxilic acid was given in the dose of 240 mg/day. The results showed, after treatment, an emphasized middle volume increase of the excreted bile, as well as a significant decrease of the biliary cholesterol, while pH and density maintained constants. The results corroborated the pharmacodynamic activities given to cicloxilic acid as a "true" choleretic to be utilized in clinic situations where it's wished a biliary flow increase and the possibility to avoid a cholesterol lithiasis or relieve consequent disturbances.

Aged↗