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Biomedical subjects

M Taddeo

Publications and source records attributed to M Taddeo.

7 recordsLinked to original sources
PubMed1989

Effects of two cocktails on left ventricular diastolic function in normal men.

The effects of alcohol on diastolic function in normal males are unknown. Therefore, 12 male physicians had a Doppler echocardiogram performed in order to assess left ventricular diastolic performance. They then drank 4 ounces of whiskey, and forty-five minutes later a repeat Doppler echocardiogram was obtained. All the Doppler indexes of diastolic performance differed significantly after the ingestion of alcohol. The mean control D-F interval was 203 +/- 26 ms and after alcohol it was 237 +/- 51 (p less than 0.01). The mean control EF slope was 4.4 +/- 0.35 m/s2 and after alcohol it was 3.2 +/- 0.73 (p less than 0.01). The control E-F interval was 114 +/- 30 ms and it increased after alcohol to 150 +/- 37 (p less than 0.001). The mean control E wave was 0.54 +/- 0.10 m/s and after alcohol it was 0.43 +/- 0.07 (p less than 0.01). The mean control A wave was 0.30 +/- 0.04 m/s and after alcohol it was 0.35 +/- 0.04 (p less than 0.01). The mean control E/A ratio was 1.80 +/- 0.20 and it fell to 1.25 +/- 0.23 after alcohol ingestion (p less than 0.001). Thus, the results suggest that 4 ounces of whiskey can produce, in normal males, a significant impairment in diastolic function.

Adult↗
PubMed1988

Pulse generator failure due to blunt trauma.

This case describes a 69-year-old male who had a permanent pacemaker implanted for sick sinus syndrome. He was struck by a car with a resultant failure of the pulse generator. Trauma-related failure of a pulse generator is a rare event. Its recognition is imperative in the overall management of the trauma patient.

Accidents, Traffic↗
PubMed1988

The resting cardiointegram: correlation with stress thallium perfusion studies.

The cardiointegram is a noninvasive technique for the analysis of the electrical signals of the heart obtained by a transformation of the voltage versus time format by a series of integrations. The stress thallium perfusion study is a widely used test for the detection of coronary artery disease. In order to evaluate the correlation between the resting cardiointegram and the stress thallium 201 perfusion study, 20 patients with normal resting electrocardiograms underwent stress thallium tests and resting cardiointegrams. The cardiointegram was determined on two resting complexes of leads I, II, V4, V5, and V6 and called abnormal if five of ten complexes deviated outside a normalized template. There was concordance of the cardiointegram and the thallium study in 16 of 20 patients (80%). The sensitivity for the detection of coronary artery disease was 71%, and the specificity was 80%. The overall accuracy was 74%. Thus in patients with normal electrocardiograms, the cardiointegram is a useful noninvasive test for the detection of coronary artery disease.

Coronary Disease↗
PubMed1988

Routine reduction of pulse generator voltage.

The porous-tip electrode has led to a significant advancement in pacing system technology. Experience with 38 patients with unipolar tined CPI porous endocardial electrodes, is reported. All patients had programmable pulse generators, CPI model number 531. The voltage in this pulse generator can be reduced from 5 to 2.5 volts. The pulse width threshold (PWT) at implantation was 0.06 ms at 5 volts in all 38 patients, and the PWT at implantation varied between 0.06 and 0.16 ms at 2.5 volts, with a mean PWT of 0.092 +/- 0.026 ms. The 38 patients were restudied six months later. The mean PWT measured at 5 volts was 0.076 +/- 0.018 ms. The PWT measured at 2.5 volts varied between 0.08 and 0.30 ms with a mean PWT of 0.178 +/- 0.067 ms. Twenty-three patients were restudied one year after lead implantation. The PWT measured at 2.5 volts varied between 0.08 and 0.30 ms with a mean PWT of 0.156 +/- 0.061 ms. All of the pulse generators were reprogrammed to 2.5 volts. This permitted a substantial prolongation of the pulse generator life (three to five years) with an improvement in the cost effectiveness of the pulse generator.

Electrodes↗