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Biomedical subjects

M Take

Publications and source records attributed to M Take.

28 records · Page 2Linked to original sources
PubMed1982

Long-term follow-up of electrocardiographic findings in patients with acute myocarditis proven by endomyocardial biopsy.

Sixteen cases of acute myocarditis, proven by endomyocardial biopsy, of possible viral origin which were described in a previous paper have been followed up for up to 5 years. The cases were divided into 3 groups according to the electrocardiographic (ECG) patterns: with conduction disturbance at the early stage (Group I, 9 cases), without conduction disturbance (Group II, 4 cases); early death cases in which the follow-up could not be carried out (Group III, 3 cases). In Group I, 2 cases revealed persistent complete A-V block, 4 showed incomplete recovery of right bundle branch and/or fascicular blocks, and 3 showed complete recovery of the ECG abnormalities. In Group II, all 4 cases showed a pseudoinfarction pattern which consisted of abnormal Q waves, poor R wave progression and ST elevation. These findings disappeared during the follow-up period. All patients of Groups I and II are still alive after a follow-up period of up to 5 years.

Acute Disease↗
PubMed1981

Early clinical profiles of cases with histopathologically proven acute idiopathic myocarditis and a proposal for diagnostic criteria.

The early clinical features, primary care, treatment and short-term prognosis in 15 cases of acute myocarditis where diagnostic confirmation was made by endomyocardial biopsy or autopsy were analyzed. Characteristically, idiopathic myocarditis of possible viral etiology revealed preceding symptoms which consisted of flu-like symptoms, i.e., fever, upper respiratory infection (sore throat, cough), myalgia or arthralgia, general malaise, and gastrointestinal disorders (vomiting, anorexia, nausea, abdominal pain and soft stool). A severe cardiac or generalized disease condition may follow. Depending upon the progress of intensive medical and cardiac care, the patients' prognosis is not always poor. Diagnostic criteria based upon our own experience have been constructed as a proposal.

Acute Disease↗
PubMed1981

[Use of cefroxadine dry syrup in the management of acute skin infections in children (author's transl)].

1. Cefroxadine dry syrup was in principle administered at the dosage of 10 mg per kilogram of body weight 3 times a day. 2. Evaluation was done in 4 grades, i.e. excellent, good, fair and poor. 3. According to subjective judgement by attending doctors, 'excellent' or 'good' was recorded in 90.7%. 4. If the evaluation was partially standardized, 'excellent' or 'good' was obtained in 74.8% of total 163 cases and in 78.7% of 108 impetigo cases. 5. Side effects were observed in 3 cases (diarrhea 1, fever 2). No direct correlation of these complaints with the administration of the present drug was confirmed.

Abscess↗
PubMed1980

Clinical and histopathological profile of sarcoidosis of the heart and acute idiopathic myocarditis. Concepts through a study employing endomyocardial biopsy. II. Myocarditis.

Through an approach employing endomyocardial biopsy, early diagnosis of acute idiopathic myocarditis is possible. The histopathological findings consisted of fragmentation of muscle bundles, degenerative changes with lysis of myocytes and interstitial mononuclear cell infiltration. The cells were irregular in size and shape and contained slightly basophilic cytoplasm or were mixed with small round cells. Early clinical symptoms consisted of flu-like symptoms, i. e., higher fever, myalgia, malaise and arthralgia. Initial ECG changes consisted of complete A-V block in 9, bifascicular block in 3, and intraventricular conduction disturbance in 4 cases. Serial biopsies were performed at the early (0--2 weeks), middle (2--4 weeks), and late stages (more than 4 weeks) in 6 cases. Two of these biopsies were performed in 6 cases and all 3 were performed in one case. The numerous interstitial cell infiltration had almost disappeared by the early stage. At the late stage, either a slight or moderate degree of interstitial fibrosis was observed. These observations coincided well with the improvement of the ECG findings. Characteristic laboratory findings consisted of high LDH, GOT, and serum amylase levels. Varieties of treatments such as temporary cardiac pacing, peritoneal or hemo-dialysis, vasodilator therapy effectively to relieve the grave clinical condition. It is concluded that acute myocarditis may heal with remarkable improvement when the appropriate treatment is applied at the early stage of the disease.

Acute Disease↗