PubMed Health⌕ Search

Biomedical subjects

M Teichert

Publications and source records attributed to M Teichert.

6 recordsLinked to original sources
PubMed1996

Multinucleated giant cell formation of swine microglia induced by Mycobacterium bovis.

Multinucleated giant cells (MGC) have been long recognized as a histopathologic feature of tuberculosis, yet little is known about the underlying mechanism of tubercle bacillus-induced formation of these fused macrophages. The main purpose of this study was to characterize cellular mechanisms involved in MGC formation of swine microglia, the resident macrophages of the brain, in cultures containing nonopsonized Mycobacterium bovis. Within 2 h of incubation, MGC were readily detected in these cultures by light and transmission electron microscopy. MGC formation was blocked by anti-CD14 and anti-CD18 antibodies and by thalidomide, a potent inhibitor of tumor necrosis factor-alpha (TNF-alpha) production my microglia. Also, TNF-alpha alone induced MGC formation. These findings suggest that two microglial cell receptors, CD14 and a beta2 integrin, and the cytokine TNF-alpha participate in M. bovis-induced swine microglial MGC formation.

Animals↗
PubMed1991

[Psychosocial stresses after hospital admission--a comparison of internal medicine and surgical patients].

56 patients have been interviewed about their psychosocial situation at the beginning of their treatment in a medical department, 62 patients in a surgical department of a General Hospital. The "medical" patients were severely disturbed by their illness and by the different diagnostic and therapeutic procedures, even by routine investigations. The "surgical" patients, who just had been operated, concentrated with their feelings on the surgical operation. The clinical atmosphere and the relation and communication to the hospital staff had similar effects on both groups. Further investigations concerning the illness and the treatment should be specified in the different clinical disciplines, while disturbances by the hospital surrounding can be asked at all patients in the same way.

Adaptation, Psychological↗
PubMed1973

[Ear-drops].

Explore the source record for details and available documents.

Anti-Bacterial Agents↗