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Biomedical subjects

M Teichner

Publications and source records attributed to M Teichner.

9 recordsLinked to original sources
PubMed1990

Systemic lupus erythematosus in dogs: association to the major histocompatibility complex class I antigen DLA-A7.

The DLA-A,B antigens and the allotypes of the fourth complement component have been determined in German shepherd dogs suffering from systemic lupus erythematosus. We have typed 26 unrelated affected dogs, 11 animals of a three generation family, and 16 dogs of a colony with a high frequency of the disease. The results obtained from the 26 unrelated diseased dogs were compared to those determined in the 23 unaffected German shepherds. The antigen DLA-A7 was found to be predominant in the diseased group with a c2 = 11.02, Pc = 0.02, and a relative risk for the carriers of 11.93. The antigens DLA-A1 and DLA-B5 were negatively associated to the disease (c2 = 14.95, Pc = 0.001, and c2 = 17.16, P = 0.0008 respectively) and thus may be of protective nature. These data were further substantiated by the typing of the three generation family and the colony.

Animals↗
PubMed1988

Spontaneous familial systemic lupus erythematosus in a canine breeding colony.

A colony of German shepherd dogs was studied in which a high proportion of antinuclear antibody (ANAb) carriers and dogs with systemic lupus erythematosus (SLE)-like signs were found. The titre of serum thymulin and the percentage of circulating T lymphocytes were both low. The incidence of disease decreased down the generations through the introduction of outside sires, thus suggesting a genetic origin for the disease.

Animals↗
PubMed1987

[Informing the patient about alternative surgical methods of delivery].

The article discusses a judgment passed by the Düsseldorf Supreme Court on 30 January 1986. An obstetrician had resorted to vacuum extraction during multiple birth (twins) because one twin was in imminent danger of hypoxia. It was found only later that during this procedure he had caused a fracture of the parietal bone with subsequent subdural hematoma. This damage inflicted on the infant had initially remained unnoticed and resulted in hemiplegia of the left side. The infant, legally represented by his parents, filed a suit for compensation against the Board of Governors of the hospital. The Düsseldorf Supreme Court ruled on 30 January 1986 that the respondent was liable to compensation. The Court was convinced that the consent obtained from the infant's mother to proceed with vacuum extraction had been invalid at that time because the physician had failed to draw her attention beforehand to the available alternative surgical method of delivery, namely, to Caesarean section. Hence, the Court argued, the procedure followed during birth was against the law so that the Board of Governors was directly liable independent of whether the responsible obstetrician had or had not been guilty of malpractice. In addition, the liability of the Board of Governors follows from the fact that the infant had not been examined by a paediatrician immediately after birth as would have been mandatory had delivery been conducted lege artis.(ABSTRACT TRUNCATED AT 250 WORDS)

Extraction, Obstetrical↗