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Biomedical subjects

M Tenhu

Publications and source records attributed to M Tenhu.

10 recordsLinked to original sources
PubMed1986

Adult polycystic liver and kidney diseases are separate entities.

In 22 cases of either adult polycystic liver (PLD) or polycystic kidney (APCD) disease, considered as one dominantly inherited entity, both diseases occurred together only once. Early microscopical cystic lesions that are typical of PLD were found in another case of APCD. In this medicolegal autopsy series the incidence of PLD was 0.05% and that of APCD 0.08%. Cerebral haemorrhage or cerebral aneurysms were found in 50% of APCD cases but in none of the cases with only PLD (p less than 0.01). Of the cases with PLD, 50% had associated renal cysts and 10% of the cases with APCD had associated liver cysts. The same medicolegal autopsy material yielded a prospective series of 95 male cases, where, however, kidney cysts were normally present in over 50% and liver cysts in about 20% of the cases of similar age. Thus, a part of the association between cystic disease of the liver and kidney may have been based on the common occurrence of cysts in old age. V. Meyenburg's complex was the microscopic alteration associated with cysts in PLD. It was associated as well with liver cysts in APCD suggesting that an intricate relation between PLD and APCD does occur in part of the cases, in this series characterized by large size APCD kidneys. The results indicate that in adults PLD is an entity of its own, expressed in most of the cases independently of APCD.

Adult↗
PubMed1975

Comparative study on the underlying cause and mode of death established prior to and after medicolegal autopsy.

A comparative study was made on the underlying cause and mode of death determined in 600 consecutive cases by forensic physicians before and after medicolegal autopsy. All available information including police records, medical documents of decedents and the results of the external medicolegal examination of the corpse were utilized to determine the cause and mode of death before autopsy. The mode of death would have been defined erroneously in 10% of cases and the underlying cause of death in 29.5% of cases if medicolegal autopsy had not been performed. The present results are consistent with previous studies which indicate that the determination of the underlying cause of death is significantly more accurate when an autopsy is performed. They also suggest that in a large number of routine medicolegal cases a similar trend, but at a lower rate, is associated with the determination of the mode of death.

Accidents↗
PubMedDate not supplied

Deaths from ischaemic heart disease in Helsinki in the years 1959-1968. Vital statistics and medico-legally autopsied sudden deaths.

According to the official vital statistics, altogether 10910 deaths from ischaemic heart disease (IHD) occurred in persons resident in Helsinki during the 10-year period 1959-68. A significant increase was found in the incidence of IHD deaths in both sexes even though changes in the structure of the population were taken into account. The increase in the age-dependent incidence of IHD deaths was most conspicuous at middle age in both sexes and in young males. Altogether 3044 IHD deaths occurring unwitnessed or within 24 hours of the onset of the fatal attack were autopsied medico-legally during the 10-year period of the study. The medico-legally autopsied cases obviously represented a high proportion of sudden IHD deaths occurring outside hospitals in Helsinki. A clear male preponderance was found in the autopsy material as compared with all IHD deaths. The prevalence of cases of acute myocardial infarction varied in different years from 27 to 49 percent at medico-legal autopsies. No significant change occurred during the 10-year period in the distribution of the medico-legally autopsied IHD deaths into social groups, in the suddenness or place of death. The home was the most common place of death. From 1963 onwards the patients dying from an ischaemic heart attack during transportation to hospital or in an outpatient department constituted 6-7 percent of all annual IHD deaths.

Acute Disease↗