[Research methods in psychoendocrinology].
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Biomedical subjects
Publications and source records attributed to M Teodoru.
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In the territory of 5 anti-TBC dispensaries in the area of Bucharest 2 circumscriptions have been selected at random in which radiophotographic detection was to be carried out integrally and 2 other circumscriptions were selected for the investigation of groups at high risk of developing tuberculosis. All the new cases of active pulmonary tuberculosis that have been recorded, through all the methods in these 20 circumscriptions in 1973 were analized retrospectively and the reasons appeared that had determined their existence was mentioned or was ommitted on the occasion of previous investigations. These reasons were correlated with the data concerning the method for detection that had been employed, according to the indications of the tuberculosis dispensaries. In view of the evaluation of the degree of real covering of the population in integral rf investigations, the team of the Institute of Phtysiology investigated representative lots of population from each dispensary and checked the catagraphy of the population in the field, house-by-house. It was noted that 20--21% of the subjects that had been programmed for the integral rf examination (according to catagraphic criteria) were absent when the checking in the field, that should have been programmed, were not included in the catagraphy. On the basis of this study the methodology for radiophotographic detection for groups with risk of developing tuberculosis was established.
Following several organized detection campaigns it was demonstrated that these did not provide valid results even when these were organized as integral detections or for groups at risk. The authors maintain that the only group in which a satisfactory result can be obtained is represented by the subjects showing symptoms evoking pulmonary tuberculosis. These are known and can be sent to investigation by the district physician. It is recommended that the radiophotographic equipments should be assimilated to radiological apparatuses, but with better accesibility which the physicians should be able to apply without difficulty in the cases with major or minor symptoms suggesting specifical pulmonary disease.
The efficiency of organized detections in an area with low phtysiogenic potential fell progressively over the last five years while the efficiency of spontaneous detections rose significantly in patients with apparently non-specific respiratory symptoms. In the districts with low incidence radiophotographic actions were not very frequent and the covering of the whole population was rather low. In contrast good results were obtained in the general network in connection with subjects with respiratory symptoms. For the districts with high endemics integral detection is recommended.
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A number of 170 relapses have been recorded between 1966 and 1975 in the sector nr. 1 of Bucharest. Of a total of 119 files that were examined a number of 11 false relapses have been selected. The authors stress the difficulties of a definite diagnosis when bacteriological confirmation in lacking, as well as previous radiological documents, and when sputum cannot be collected for bK examination. With regard to pulmonary tuberculosis involving the pleural cavity, repeated examinations of the pleural fluid are necessary, and especially pleural bioptic puncture. Relapses in pulmonary tuberculosis represent an epidermiometric index, and especially an index of efficiency of the anti-tuberculous therapy. Recording and reporting of these categories of patients is of particular importance in the evolution of the tuberculous endemy, and has special significance for the patient (that has to carry out a 12 month treatment with its social, economic and psychologic effects) and for the contact cases.
An analysis is made of cases of pulmonary tuberculosis that have been confirmed bacteriologically, as well as from the point of view of the incidence, of the prevalence and of the dynamics of the contaminating reservior. The generally favourable evolution of these indices is stressed evidencing the great danger of contamination of new cases before these patients are detected. The necessity is also stressed of a continuous improvement in the case-finding and diagnostic activity.