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Biomedical subjects

M Thiery

Publications and source records attributed to M Thiery.

At least 19 recordsLinked to original sources

[The inventors of the obstetric forceps and the obstetric lever].

A multiple lineage is proposed for the invention of the obstetric forceps. Having been conceived by a member of the Chamberlen family in fifteenth- or seventeenth-century England, the instrument seems to have been reinvented in Flanders by Jan Palfyn and in Holland by Rogier Roonhuyse. Later, Roonhuyse invented a more effective instrument for coping with the impacted head: the obstetric lever. Palfyn's "Iron Hands" inspired Dussé to produce the "French" forceps which bears his name.

Belgium

Social differences in low birthweight and preterm deliveries in twins.

The relationship between low social class and low birthweight or preterm deliveries is well established in singletons but not in twins. We present a study using all twin deliveries registered in Belgium in 1983 and in Aberdeen between 1951 and 1983. No significant relationship was found between social class and low birthweight, very low birthweight or preterm deliveries in the Belgian sample. In Aberdeen, we found significantly higher rates of low birthweight twins in low social classes. This increase of low birthweight twins in low social classes occurred in Aberdeen during the period 1951-1968, but not in the more recent data.

Belgium

[Cocaine and pain control in childbirth].

Without absolutely any pain, women can live through the whole process of birth-giving thanks to the discovery of cocaine (1860) and the work of surgeons and obstetricians, who invented a whole range of locoregional methods, and the chemists who delivered them safe substitutes for cocaine. It was, as a matter of fact, a long way to go, but the final result was surely worth the effort.

Anesthesia, Obstetrical

[Midwifery education in Ghent: a historical sketch].

In spite of the tremendous importance of the services of the midwife in past centuries, formal regulation of their office was delayed until the establishment of the Collegium Medicum Gandavense (1663). Formal instruction of Ghent midwives was belated even longer, the first school for midwives being established only in 1772. Two years later, the Castellania Auderburgensis started her own school for midwives, the Ecole Royale et Supérieure d'Accouchements. Thus, it was Ghent's unique privilege to possess two schools for midwives in the latter fourth of the 18th century, one supervised by the city's medical college, the other by the Castellania of the Oudburg. Due to the charisma of its teacher (the famous man-midwife J.B. Jacobs) and thanks to the fact that the jurisdiction of the Castellania comprised the greater part of the present-day provinces of East- and West-Flanders, the Ecole Royale became a tremendous success. Unfortunately, this school was short-lived: together with the Castellania it was suppressed by the French in 1795. The City School fared better. Indeed, its teacher (med. lic. Damman), by joining the Comité de Santé of the Département de l'Escaut could rescue the institution and bridge the gap between the suppression of the Collegium Medicum Gandavense (1795) and the foundation of the Ecole de Chirurgie by the French administration (1801). Both the Ecole de Chirurgie and the other French "medical" schools of Gent [Ecole de Médecine, de Chirurgie et de Pharmacie (1805-1806) and Ecole élémentaire de Médecine (1806-1817)] took care of the theoretical instruction of departmental midwives. Regretfully, the authorities did fail to make use of the opportunities granted by the French law and establish a "home for poor women" in their city. Had such been realized, midwives would have had a chance to obtain clinical training as well. For the latter we will have to wait another decade. Indeed, it was only at the end of his reign that king William I succeeded to persuade the local and provincial authorities of the dire necessity of establishing a maternity clinic with annexed school for midwives. The first Provincial Maternity Clinic was installed in 1828 in a building erected for this purpose at the Hoveniersdreef. Two years later, the medical students of the Ghent State University (founded by William I in 1817) were admitted to the school for clinical teaching, be it in separate quarters. Because the main purpose of the Maternity Clinic was the instruction of midwives, the medical faculty will be treated as "parente pauvre" for decades to come.(ABSTRACT TRUNCATED AT 400 WORDS)

Belgium

Perinatal hazards of chronic antenatal tocolysis with indomethacin.

Indomethacin was administered from the 20th to the 34th week of gestation to 51 women (59 fetuses) in whom bed rest and a beta-mimetic compound (ritodrine) had failed to stop preterm labor. No serious maternal side effects were observed. Of the 8 perinatal deaths, 5 were not and 3 were possibly related to the prostaglandin synthesis inhibitor. The sole case of serious neonatal morbidity is not considered to have had a causal relationship with the indomethacin treatment.

Adult

Immediate postpartum insertion of a copper-wired intrauterine contraceptive device, the MLCu250.

The MLCu250, a copper-wired intrauterine contraceptive device, was inserted in 600 women immediately after delivery of the placenta. Thirty months after insertion, 9843 woman months of experience were computerized and the data analysed according to the life-table method. The gross cumulative pregnancy and expulsion rates were 1.3 and 6.0 respectively. No serious complications were observed and the puerperium was uncomplicated.

Adult

Puerperal lactation suppression and prolactin.

Five methods for puerperal lactation inhibition were assessed in a randomized fashion. The 90 women were divided into five groups. Four of these received a pharmacologic treatment: oral stilbestrol (15 mg dd for 5 days), a diuretic compound (bendroflumethazide 15 mg dd for 5 days) by mouth, oral bromocriptine (5 mg dd for 14 days), or an intramuscular injection containing estradiol (10 mg and testosterone (200 mg) esters administered immediately after delivery. To the women in the remaining group only physical methods were applied (breast support and local infra-red waves) and they served as controls. Prolactin plasma concentrations were determined daily for five consecutive days and showed a correlation with the clinical effectiveness of the various treatment schedules. While bromocriptine reduced and stilbestrol augmented prolactin levels, both types of treatment were equally effective in preventing lactation during the observation period. Treatment with a diuretic compound or with an injection of steroids, though less effective than the first two regimens, was nevertheless significantly more efficacious than physical treatment.

Bendroflumethiazide

Vaginal prostaglandin E2 for interruption of pregnancy and management of intrauterine death.

Vaginal suppositories containing 20 mg prostaglanding E2, administered at 2-5h intervals, are very effective in interrupting second-trimester pregnancy and in inducing labor in case of death in utero. However, side effects are common and make the treatment unpleasant to most patients. Premedication with an maintenance of a potent anti-emetic (e.g. haloperidol) and an anti-diarrheic (e.g. loperamide) considerably reduce the frequency and severity of these side effects.

Abortifacient Agents, Nonsteroidal

The effect of locally administered estrogens on the human cervix.

A randomized study to evaluate the effect of natural estrogens on the unripe uterine term cervix was conducted. One hundred and five term gravidas were studied, of whom 70 were treated with 180 mg 17 beta-estradiol or 250 mg estriol (treated women) and 35 were treated with gel only (control group). In all subjects the distented Foley catheter used for the instillation was left in situ. Twelve hours after the instillation there was no apparent difference in mean cervical progress between treated women and controls and the rather unexpected degree of cervical ripening is atributed to the intra-uterine balloon catheter. The procedure could not be shown to have any untoward effect on the mother or the fetus.

Acid-Base Equilibrium