[Rapid determination in the blood of sodium and potassium electrolytes, by means of the electrometric method and the use of glass electrodes].
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Biomedical subjects
Publications and source records attributed to M Tiengo.
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BACKGROUND: 1) To analyse the information provided both by the Visual Analogue Scale (VAS) and by the McGill Pain Questionnaire (MPQ) in a cross-sectional study with patients affected by different kinds of pain and to study the relationship between VAS and MPQ scores in the same patient sample. METHODS: 962 patients affected by different kinds of pain (i.e. neuropathic pain, acute post-traumatic pain, chronic musculo-skeletal pain, headache, and cancer pain) were enrolled into the study during the first visit for pain management. The horizontal 10cm VAS and the Italian version of the MPQ were administered. RESULTS: VAS scores proved to be significantly lower in acute post traumatic and in chronic musculo- skeletal pain compared to headache and neuropathic pain. VAS scores were signi- ficantly higher in neuropathic pain compared to cancer pain. MPQ total score (Pain Rating Index, PRI) related to neuropathic pain was significantly higher than scores reported in the other pain groups, with the exception of cancer pain. Cancer pain MPQ total score was higher than acute post-traumatic and chronic musculo-skeletal PRI pain scores. Different patterns of MPQ dimensions emerged within each pain group. The association between VAS and PRI, analysed by means of stepwise multiple regression analyses was significantly different among the groups (p<0.0001). The percentage of VAS variance explained by MPQ PRI score ranged from 6% (headache) to 32% (neuro-pathic pain). CONCLUSIONS: Several differences emerged among the pain groups. VAS and MPQ resulted to address pain aspects only partially overlapping. In some clinical conditions (headache and cancer) the MPQ can provide more detailed and clinically useful information about patients' pain experience.
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The four main descending pathways - from the cortex, the diencephalon, the mesencephalon and the pontobulbar structures - are briefly examined with regard to their role as regulatory systems with an overall inhibitory action processing the afferents to the spinal cord. Sketches are given of the possible analgesic properties in the selective gating of C and Ad nociceptive afferences. The involvement of neuronal subpopulations in the spinal cord presenting alpha-2 and alpha-1 receptors, their hypothetic role in certain reactive analgesic processes, and their coactivation are mentioned briefly.
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