PubMed Health⌕ Search

Biomedical subjects

M Tokosová

Publications and source records attributed to M Tokosová.

12 recordsLinked to original sources
PubMed1990

[The effect of cyadox and virginiamycin on Marek's disease in chickens].

Chickens infected with highly virulent Marek's disease virus were administered in the course of 56-day fattening cyadox at a dose of 20 mg per kg feed mixture (MC group). and virginiamycin at a dose of 10 mg per kg feed mixture (MV group). The weight gains on the 56th day and dressing percentage were highest, in comparison with the control group (711.11 g and 60.62%), in the virginiamycin-treated group. An investigation into the basic chemical composition of meat revealed lower contents of dry matter and proteins in the virginiamycin-treated group (26.9% and 22.76%) if compared with the control group of chickens which were also infected with Marek's disease virus. A biometrical examination of the organs showed a statistically significant decrease in heart weight in the cyadox-treated group, increase in liver and heart weight and intestine shortening in the virginiamycin-treated group, in comparison with the control group. Pathologico-anatomical changes typical of Marek's disease were recorded in a randomly selected number of chickens in 33.3% in the control group, in 28.5% in the cyadox-treated group and in 50.0% in the virginiamycin-treated group.

Animals↗
PubMed1990

[Superovulation induction in sheep using PMSG].

The effects of application of differentiated PMSG rates (Antex Leo, Denmark) were investigated in 30 ewes of the Slovak Merino breed in the period of May--June in experimental conditions on the induction of superovulation and on the speed of egg transport through the sexual organs. After administration of PMSG at rates of 750, 1000 and 1500 i. u. per head/day, increases were recorded in the average weight of ovaries, number of large follicles and ovulations. Flushing the eggs from different parts of the sexual organs indicated that the higher the PMSG rate, the faster was the egg transport.

Animals↗
PubMed1990

[Quantitative micromorphological study of the ovaries in sheep after estrus synchronization and superovulation in the autumn mating season].

The quantitative micromorphological changes of tertiary follicles and corpora lutea (CL) were studied in ewes in the autumn mating season after oestrus synchronization, induced by administration of PGF2 alpha (Oestrophan Spofa) at a rate of 125 micrograms, and after superovulation, induced by administration of PMSG (Antex Leo, Denmark) at a rate of 1000 I. U., or PMSG at rates of 750 and 1000 I. U. together with 50,000 I. U. vitamin A (Axerophthol Spofa). The highest number of ovulations was obtained in ewes treated with 1000 I. U. together with vitamin A (3.4 +/- 3.0) and after administration of 1000 I. U. PMSG alone (2.6 +/- 2.74). The highest number of tertiary follicles was recorded in ewes after administration of PGF2 alpha. The proportion of tertiary atretic follicles was the highest in ewes after administration of PMSG (64.6%). The occurrence of the luteinizing form of atresia was recorded only in ewes treated with PMSG (4% of the total number of atretic follicles). Using the caryometric analysis of the luteal cells of corpora lutea, the ewes of the experimental groups had two-peak variation curves; this corresponds to the theory of the presence of two luteal types in the tissue of the corpus luteum in ewes. As determined morphometrically, the smallest proportion of connective tissue out of the total volume of ewes' ovaries was found after administration of 1000 I. U. PMSG together with vitamin A. Administration of vitamin A together with PMSG had a favourable influence on the over-all follicular response, on the average number of ovulations, and on the proportion of non-atretic follicles.

Animals↗
PubMed1990

[Changes in the biometry of the sex organs of sheep after estrus synchronization and superovulation in the breeding period].

In twenty ewes of the Slovak Merino breed coming from a demonstration farm at Zemplínska Teplica, to the age of two-three years biometrical variations of the sex organs and overall follicular response to PMSG and PGF2 alpha administration were investigated in the autumn period (October-November). In the ewes of all groups the heat was synchronized by i. m. administration of PGF2 alpha (Oestrophan Spofa) at a dose of 125 micrograms in the interval of 11 days. On the ninth day the ewes of the second and fourth group were given 1000 i. u. of PMSG (Antex Leo, Denmark), the ewes of the third group 750 i. u. of PMSG. The ewes of the third and fourth group were administered at the same time 50,000 i. u. vitamin A (Axerophtol Spofa) (each group). The weight and dimensions of the sex organs were investigated. The results demonstrate that the administration of PMSG in the mating period increases significantly the weight of oviducts and horns of uterus in the ewes while there are no variations of the weight of the other sex organs and of their length, or it is lower than in the ewes of the control group. The overall follicular response was not influenced by the higher weight of ovaries.

Animals↗
PubMed1990

[The effect of the seasons on the ovarian response in sheep after the administration of the serum gonadotropin, PMSG].

In the autumn oestrus season, 20 Slovak Merino ewes were exposed to synchronization of oestrus, treated with the PGF2alfa at doses 125 micrograms (Oestrophan, inj. Spofa). followed by an injection of PMSG at doses 1000 IU (Antex Leo Denmark) and 50,000 IU of Vitamin A (Axerophtol Spofa). 23 anoestrus ewes were synchronized with an intravaginal sponges containing 20 mg of chlorsuperlutine (Agelin, Spofa) for 12 days and after sponge withdrawal, the ewes were injected with 750 and 1000 IU of PMSG (Antex Leo Denmark). Ovulatory response was observed and the possibility of ova recovered from the genital organs in ewes after synchronization of oestrus and superovulation in oestrus season. Higher values of the total follicular response (CFO), and the average number of ovulation (PO) after administering equal doses of PMSG were found out both in anoestrus ewes (CFO 6.62 +/- 4.24; PO 4.25 +/- 4.52) and in oestrus ewes (CFO 2.70 +/- 2.10; PO 2.60 +/- 1.74; resp. CFO 2.80 +/- 1.83; PO 3.4 +/- 3.0), if the ewes were treated with PMSG together with vitamin A. The average number of ova flushed was higher in anoestrus ewes (3.0-0.5) than in oestrus ewes (1.67-3.75). In both trials the equal ratio in the number of released ova was gained from ewes of experimental groups (83-88% of the total number). After ova flushing from the genital organs in ewes of the experimental groups most ovas were found in the isthmatal part of the uterine tube (36-60%). On the basis of gained results it was concluded, that synchronized oestrus ewes on receiving PMSG in anoestrus season the ovarial response was more significant than in autumn breeding season.

Animals↗
PubMed1989

[The effect of growth stimulators on the levels of various macroelements in chickens].

Nitrovin administered at the dose of 15 mg per 1 kg of diet, cyadox (20 mg) and virgiamycin (10 mg) were studied as to their effect on the contents of calcium, sodium, potassium and magnesium in the blood serum, breast and thigh muscles, and feathers of chickens. The contents of calcium, sodium, potassium and magnesium in the blood serum ranged within the physiological limits. An increased content of calcium and potassium and a decreased content of sodium were recorded in the breast and thigh muscles, as compared with the control group. The contents of these macroelements in the feathers of the experimental group were significantly different from those in the birds of the control group.

Animals↗
PubMed1989

[The effect of growth stimulators on the levels of various trace elements in chickens].

Chickens, fattened for 56 days, were treated with nitrovin at the dose of 15 mg per kg of feed, cyadox at the dose of 20 mg per kg of feed, and virginiamycin at the dose of 10 mg per kg of feed. After the fattening, the chickens were studied for the contents of copper, zinc, and manganese in the blood serum, thigh muscle, breast muscle, and feathers. The contents of copper, zinc and manganese in the serum ranged within the limits of physiological values. As for the breast muscle, the content of copper increased but the content of manganese declined in both breast and thigh muscle, as compared with the control group. The feathers contained more manganese in all the groups, as compared with the controls.

Animals↗
PubMed1989

[The effect of natural zeolite on the excretion and distribution of radiocesium in rats].

Observation was made of the influence of natural zeolite (clinoptilolite) supplement in food on 134Cs excretion and distribution after oral internal contamination of laboratory brown rats. After diet administration with 2.5, 5, and 10% zeolite supplement the 134Cs elimination in droppings increased and the radionuclide deposition in liver, kidneys and femoral musculature decreased. The zeolite decontamination effects were observed with preventive administration, as well as with sorbent administration from the 24th hour after a single internal contamination.

Aluminum Silicates↗
PubMed1989

[Use of nitrovin in feed and its effect on the development of Marek's disease in chickens].

The effect of the Czechoslovak product Nitrovin, administered at a rate of 15 mg per kg of feed mixture, was studied as exerted on the growth activity, meat quality, and the development and intensity of occurrence of patho-morphological changes ascribable to Marek's disease. An increase of weight gains and dressing percentage was recorded in the group of birds given Nitrovin, as well as in those which had Nitrovin in their feed and were infected with a highly virulent virus of Marek's disease. No significant changes occurred in the contents of dry matter and protein, but there was a much lower fat content in breast muscle in the groups of chickens infected with the Marek disease virus. Internal organs were subjected to biometrical measurements. The birds treated with Nitrovin and infected with the highly virulent virus of Marek's disease had significantly lighter hearts and heavier spleens. Liver, nervus ischiadicus, gonads and spleen were affected most intensively by the changes testifying to Marek's disease. The results are just preliminary and the investigation continues.

Animal Feed↗
PubMed1989

[Contamination of food with cesium radionuclides].

Specific activities of 134Cs, 137Cs were investigated and compared in canned meat products, pork, beef, poultry, venison, as well as in raw cow milk, milk products and milk replacers. Increased specific activities of cesium radionuclides in canned meat products were found up to 70 Bq.kg-1 in 1986, up to 150 Bq.kg-1 early in 1987, and a gradual decline of specific activity to 40 Bq.kg-1 at the end of 1988. In 1987 these values made up to 50 Bq.kg-1 and 120 Bq.kg-1 in pork and beef, up to 30 Bq.kg-1 in poultry, and up to 160 Bq.kg-1 in venison. In 1988 a decrease in these specific activities occurred down to 30 Bq.kg-1. The values of 134,137Cs specific activity did not exceed 10 Bq.kg-1 in raw cow milk, and 30 Bq.kg-1 in milk products. Specific activity up to 200 Bq.kg-1 was found in milk replacers.

Animals↗