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M Tommasi Rosso

Publications and source records attributed to M Tommasi Rosso.

4 recordsLinked to original sources
PubMed1998

[Comparative study of preemptive and postincisional lumbar epidural morphine in pulmonary resection. Preliminary report].

OBJECTIVES: To evaluate the efficacy and incidence of side effects of two types of lumbar epidural analgesia with morphine, preemptive or postincisional, combined with total intravenous anesthesia in chest surgery. PATIENTS AND METHODS: This double-blind prospective study enrolled 20 patients (ASA I-IV) undergoing lobectomy or pneumonectomy. Anesthetic induction and maintenance was provided with propofol, atracurium and alfentanil. Lumbar epidural analgesia (L2-L3) with morphine was provided for group A patients with 2 to 4 mg upon excision of tissue and for group B with 2 to 4 mg during anesthetic induction. The following variables were recorded: arterial blood gas concentrations, heart rate, SpO2, EtCO2, postanesthetic recovery, arterial gases, side effects and pain on a visual analogue scale. Top-up analgesia was provided by intravenous metamizole and/or epidural morphine. For statistical analysis we used ANOVA, chi-square tests and Student-Newman-Keuls tests. RESULTS: The need for propofol and alfentanil during anesthesia, and for morphine and metamizole after surgery were statistically greater in group A. Pain 18 hours after surgery was also greater in group A. No significant differences between groups for other variables was observed. CONCLUSIONS: Preemptive analgesia with lumbar epidural morphine in addition to the general anesthesia described here seems to provide higher-quality analgesia with few side effects, reducing the need for propofol and alfentanil during surgery and for postoperative morphine and metamizole.

Aged↗
PubMed1995

[Cardiocirculatory stability and early extubation in patients undergoing thoracic surgery with propofol as the single anesthetic agent].

OBJECTIVE: To determine the efficiency of total intravenous anesthesia technique (TIVA) using propofol on maintaining cardio-circulatory stability and rapid recovery time in patients undergoing thoracotomy. DESIGN: Prospective study. SETTING: University General Hospital in Spain. PATIENTS: Twelve patients, undergoing elective thoracic surgery, including lung resection with one-lung ventilation with more than 120 minutes of anesthetic time. METHODS: ECG, blood pressure (BP), heart rate (HR), pulse oximetry (SpO2), end tidal CO2 (ETCO2) and muscular relaxation with Relaxograph were monitored. Anesthesia was performed with propofol 1.5-2.5 mg/kg i.v. and maintained with continuous propofol infusion 4 +/- 1.4 mg/kg/h. Fentanyl, 10 mg i.v., was administered in bolus. After succinylcholine 1 mg/kg i.v. or atracurium 0.5 mg/kg i.v., trachea was intubated with a double-lumen tube or a standard cuffed endotracheal tube. The patients were ventilated with air-oxygen mixture. Maintenance of muscular relaxation was obtained with atracurium 0.2 mg/kg i.v. RESULTS: No significative differences were registered in the values of heart rate, SpO2, ETCO2 and between intraoperative blood pressure and the postextubation blood pressure values. Recovery time, from discontinuation of the propofol until postoperative extubation, was 8.25 +/- 4.8 minutes. CONCLUSIONS: Performing a TIVA with propofol good cardiocirculatory stability was obtained. Continuous monitoring of relaxation, graphically recorded, knowing the bolus rate of muscle relaxant, allows us to antagonize it totally, facilitating patient recovery and its early postoperative extubation.

Adult↗