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M Tonai

Publications and source records attributed to M Tonai.

5 recordsLinked to original sources
PubMed1999

Clinicopathological study on liver dysfunction in measles.

We analyzed the clinical course of eight patients with liver dysfunction in measles. All of the patients showed an elevation of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and lactate dehydrogenase (LDH), but no jaundice. These levels returned to normal about 3 weeks after the onset of the rash. A percutaneous liver biopsy was done in two cases. Histological examination showed slight necrosis of liver cells but no significant changes in portal area. On electron microscopy, virus particles were not detected. We detected measles virus RNA in the liver specimen by RT-PCR, which suggests that the measles virus affects liver cells directly in measles.

Adolescent↗
PubMed1982

Osteoblastoma: classification and report of 16 patients.

In 16 patients who had osteoblastoma treated within the last eight years, the lesions can be classified as vertebral (four cases), central "benign" (seven cases), "aggressive" (three cases) and periosteal (two cases). The radiographic features were highly variable except for the consistent shell of reactive periosteal bone. None of the lesions resembled osteoid osteoma or osteosarcoma. The histological pattern was typical, showing sheets of osteoblasts forming irregular, poorly ossified bone trabeculae in a fibrovascular stroma. The three "aggressive" lesions had a distinctly more ominous histologic pattern, a more destructive radiographic appearance and recurred promptly following local curettage. Treatment varied, but for the vertebral, benign "central," and periosteal osteoblastomas, curettage or marginal resection was generally curative. Local wide resection was required for individual aggressively growing tumors.

Adolescent↗