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Biomedical subjects

M Torrens

Publications and source records attributed to M Torrens.

8 recordsLinked to original sources
PubMed1992

Assessment and management of opioid withdrawal symptoms in buprenorphine-dependent subjects.

The spontaneous physical dependence of buprenorphine was assessed in opioid addicts who switched from heroin to sublingual or intravenous buprenorphine. Twenty-two patients were randomly assigned to double-blind administration of methadone (n = 11) or placebo (n = 11) for 13 days after abrupt withdrawal of buprenorphine. Methadone was administered according to four pre-established dosing schedules depending on the previous amount of daily consumed buprenorphine. No methadone-treated patient required modification of the therapeutic regimen, whereas eight of eleven placebo-treated patients needed treatment with methadone. Buprenorphine withdrawal syndrome was of opioid type, began somewhat more slowly, and showed a peak until day 5. The occurrence, time-course and characteristics of buprenorphine withdrawal syndrome make it necessary to reconsider the abuse potential of this analgesic.

Adult↗
PubMed1991

Cocaine abuse among heroin addicts in Spain.

Abuse of cocaine is becoming a major problem among heroin addicts in Spain. Between 1987 and 1988, 75% of patients admitted as inpatients for detoxification from opiate dependence had consumed cocaine during the 6 months prior to admission and 25% had abused cocaine daily or several times/week. These cocaine abusers showed more toxicologic and psychopathologic problems than opiate addicts who did not abuse cocaine. The opiate addicts who also abused cocaine had begun using illicit drugs earlier and showed a higher frequency of anti-HIV antibodies. They also had more antisocial personality disorders and persistence of depressive symptoms during opiate detoxification than heroin addicts who did not abuse cocaine. Based on these findings, we insist on the need to develop different treatments for detoxifying patients with this dual addiction.

Adolescent↗
PubMed1990

[Treatment of acute leukemia: usefulness of an immunodepressed unit].

A special unit for immune-depressed patients was used in the treatment of acute leukemia in 33 patients. Results of therapy were compared to those in 30 historical controls treated in a general ward. Both groups were comparable regarding age, sex, type of leukemia and severity of bone marrow depression. The incidence of fever and the percentage of complete remission were higher in patients treated in the unit, including patients with acute lymphoblastic leukemia. The remission rate in the subgroup of patients with acute myeloid leukemia was not improved. Mortality rates were also not different. We recommend the use of this unit for treatment of patients with acute leukemia, given the lower infection rate and the higher probability of remission.

Acute Disease↗
PubMed1979

Bladder denervation procedures.

Bladder denervation can provide useful rehabilitation of bladder function when other measures have failed. Idiopathic hyperactivity may respond best to hyperbaric distension or bladder transection. Procedures performed close to the bladder seem, at present, to be more effective than those near the central nervous system. Procedures have little morbidity, apart from transection. On the average a 50 per cent improvement may be expected, but in all cases it is most important to consider the length of follow-up in reported series.

Denervation↗
PubMed1979

Cystometry.

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Humans↗