PubMed Health⌕ Search

Biomedical subjects

M Tost

Publications and source records attributed to M Tost.

At least 37 records · Page 2Linked to original sources

[Malignant non-Hodgkin lymphomas of the orbital region. Histological classification and immunohistochemical studies].

We analysed 15 cases of malignant non-Hodgkin's lymphomas of the orbital region in a retrospective study of the biopsy material from 1965 to 1981. There were 9 cases of lymphoplasmacytic immunocytomas , 1 case of pleomorphic immunocytoma, 2 cases of centroblastic-centrocytic lymphoma and 1 case of plasmacytoma, lymphoblastoma and pleomorphic immunoblastoma . In the majority of cases the orbital region was the primary site of the lymphoma. In a minor part the lymphomas were the expression of a generalized lymphomatous disease. The 15 patients were 12 men and 3 women from 38 to 82 years of age. The peak of incidence was in the septuagenarians . In some of the cases the neoplastic nature of the lymphoproliferative disorder was proved immunohistochemically by the presence of monoclonal cytoplasmic immunoglobulin. The clinical course of the disease was very different and could not be predicted bioptically. Discussing the results we compared our own findings with those in the literature.

Adult↗

[Lymphomata and pseudolymphomata in the region of eyelid and orbital cavity (author's transl)].

The results of a retrospective study on patients with lymphomata and pseudolymphomata are presented. The interpretation of histological findings may be difficult. This is demonstrated by two cases. In both of them the histological structures in the biopsies were regarded as benign. The course of the disease however, demonstrated malignancy. The term "pseudotumour" of the orbita ought to be used carefully. The treatment and the prognosis of malignant lymphomata demand a classification, reflecting the biological behaviour of the lymphomata. Such classification was elaborated by an International group and is known as the Kiel classification. It should be applied in lymphomata of the orbital region, too. The use of an uniform classification of the malignant lymphomata is essential for all disciplines, involved in the diagnosis and treatment of the neoplasms.

Aged↗

[Prognosis of basal cell carcinoma of the eyelids in relation to histologic differentiation and thoroughness of resection].

As life expectancy increases the diagnosis and treatment of basal cell carcinoma of the lids is assuming ever greater importance. While there is still some debate as to whether conservative or surgical treatment is preferable, the emphasis in conservative treatment varies. Our own view is based on an analysis of 531 surgically treated patients. For histologic differentiation we used the data of Lever (1958). Considering that our recidivity rate was only 6.2%, we recommend primary surgical treatment. After localization of the tumor the inner canthus in particular should be kept under observation for recurrences. Histologic differentiation showed the sclerodermiform basal cell carcinoma to be especially dangerous.

Adult↗

[Enzymatic studies in lenses of different breeds of mice (author's transl)].

Leucinaminopeptidase (LAP), lactatedehydrogenase (LDH) and glucose-6-phosphatdehydrogenase (GPDH) were analysed in the lenses of two different breeds of mice. Compared to the lenses of a control stock (Agnes Blum, Jena), in the healthy seeming, heterozygous mice the same activities of LAP, LDH, and GPDH were found. But in the breed with evident microphthalmos and cataract LDH was increased. Possible connections are discused.

Animals↗