PubMed Health⌕ Search

Biomedical subjects

M Tsaloumas

Publications and source records attributed to M Tsaloumas.

5 recordsLinked to original sources
PubMed1998

Evaluation of optic disc cupping using high-resolution ocular ultrasound.

BACKGROUND/PURPOSE: The new Biovision B-Scan Probe has greater resolution than its predecessors because of its posteriorly placed focus (25 mm inside the eye) and the consequent reduction in size of the sound field. We investigated the accuracy, reproducibility and test-retest variability of two-dimensional optic cup measurements using this new-generation B-scanner. METHODS: One randomly selected eye of 20 patients underwent five repeated measurements of vertical (VOCD) and horizontal optic cup diameters (HOCD), and optic cup depth, using confocal scanning laser tomography (Heidelberg Retinal Tomograph) and high-resolution ultrasound (Biovision, Chiron Vision, UK) on two separate occasions. There was one operator per instrument who was masked to all clinical data and previous measurements. Accuracy of ultrasound readings was quantified by comparing the results with those of Heidelberg Retinal Tomography (HRT). RESULTS: The 95% confidence interval for the bias of echographic vertical and horizontal cup diameter measurements was -95 +/- 48 microns and -19 +/- 72 microns respectively, and -87 +/- 328 microns for cup depth readings. The indices of reproducibility (mean coefficient of repeatability +/- SD) were: VOCD: 177 +/- 105 microns [B-scan] 209 +/- 100 microns [HRT]; HOCD: 179 +/- 61 microns [B-scan], 205 +/- 101 microns [HRT]; cup depth: 206 +/- 63 microns [B-scan], 204 +/- 124 microns [HRT]. Ninety-five per cent limits of agreements between initial and retest values for ultrasound were 18 +/- 136 microns [VOCD], 2 +/- 144 microns [HOCD] and 4 +/- 156 microns [cup depth], compared with 1 +/- 104 microns [VOCD], 20 +/- 102 microns [HOCD] and 3 +/- 168 microns [cup depth] for scanning laser tomography. CONCLUSION: The results demonstrate that measurements of optic cup diameter and depth using ultrasound correlate strongly with corresponding HRT readings. These echographic measurements are reproducible, and not subject to clinically meaningful test-retest variability. This technique of measuring two-dimensional cup parameters does not require expensive specialist equipment and has many potential clinical applications which are discussed.

Aged↗
PubMed1998

Surgical excision of subfoveal neovascular membranes.

BACKGROUND: Subfoveal choroidal neovascular membranes (CNV) are a cause of significant visual impairment. Laser treatment of such lesions results in visual loss. Surgical excision of CNV may allow stabilisation or improvement of vision. A series of results of surgical excision are presented. METHODS: The records for 43 eyes of 40 consecutive patients undergoing surgical excision of CNV not associated with age-related macular degeneration (AMD) were reviewed retrospectively. Statistical analyses of the relationship between pre-operative factors and post-operative visual results were made. Improvement or worsening of visual acuity was defined as a change of more than 2 lines of Snellen acuity. RESULTS: In 79.1% of patients visual acuity was improved or unchanged following surgery, and in 20.9% there was a reduction of Snellen acuity. There was no statistically significant association between visual outcome and age, gender, duration of visual symptoms, cause of CNV, presence of subretinal haemorrhage, elevation of retina by subretinal fluid, prior laser surgery, or the presence of pre-operative or intraoperative subretinal haemorrhage. There was a possible association between the non-use of gas tamponade and an increased chance of reduced vision. Visual loss was more likely in those eyes with good pre-operative visual acuity. Recurrence of CNV was noted in 10 (23%) eyes; repeat surgery was not associated with a worse visual outcome. CONCLUSIONS: Surgical excision of CNV not related to AMD is a promising technique. More meaningful assessment of visual function in these patients will allow refinement of case selection.

Adolescent↗
PubMed1997

Retinal haemorrhages and convulsions.

AIMS: To evaluate the incidence of retinal haemorrhages after convulsions in children. PATIENTS AND METHODS: All children who required hospital admission after an episode of convulsions were included in the study. Complete neurological and ocular examinations, including ophthalmoscopy, were undertaken within 48 hours of hospital admission. RESULTS: Thirty three children were examined according to the protocol and their seizures were classified by a paediatric neurologist. Despite the fact that some of the children also vomited or underwent cardiopulmonary resuscitation, none of the 33 children developed retinal haemorrhages. CONCLUSIONS: Convulsions rarely (if ever) give rise to retinal haemorrhages. The finding of retinal haemorrhages should stimulate a detailed assessment to exclude non-accidental injury, whatever the nature of the associated or antecedent events.

Adolescent↗