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Biomedical subjects

M Tsekov

Publications and source records attributed to M Tsekov.

11 recordsLinked to original sources

[Acute myocardial infarct in a patient with multiple sclerosis].

The authors discuss the progress of acute myocardial infarction in a male subject, aged 39 suffering multiple sclerosis for 11 years. The progress of the infarction is severe but with a favourable outcome. It comes to confirm the literature survey of the existence of a correlation between the neurologic disturbance with the accompanying disturbances in lipid, protein and carbohydrate metabolism, increased blood coagulation ability and the ischemic heart disease. The incidence (10%) of multiple sclerosis among the neurologic diseases of organic nature and the affect of people in their most productive age (20-40) and the mutual relationship with the ischemic heart disease brings for the necessity of a early detection and treatment of the present coronary insufficiency, parallelly with the basic disease, in order to improve the prognosis of those patients.

Acute Disease

[Prognostic value of SGOT, LDH and LDH1 activity in myocardial infarct].

The authors follow up SGOt, LDH and LDH1 enzyme activity in 102 patients with first transmural myocardial infarction. The results confirm the considerable diagnostic value of that enzyme spectrum and its significance for the prognostic assessment of the state of such patients. The high values of SGOT and primarily of LDH and LDH1, their persistence during the acute period of myocardial infarction correlate with the percentage of the patients with severe progress of the disease and high lethality. Prognostically unfavourable are especially the values over 800 mU/ml for LDH and 80% for LDH1. In 56.2% of the decreased LDH was over 800 mU/ml and in 70% of the decreased--80% LDH1 enzyme activity was found.

Acute Disease

[Acute circulatory insufficiency in the early phase of myocardial infarct: its frequency, clinical forms and the outcomes with 1400 patients].

The authors found acute circulatory insufficiency (cardiac asthma, pulmonary edema or cardiogenic shock in 26.2 per cent of the patients among the followed up 1400 patients with myocardial infarction. Insufficiency is more frequently met among women (36 per cent) while among men it is 22 per cent and grows with age advancing of the patients. A substantial number of the patients with acute circulatory insufficiency were admitted to the hospital in grave states, and failed to be affected by the complex therapeutic approach, and 62 per cent of them died. Total mortality rate in all 1400 patients is 28 per cent and in the patients without circulatory insufficiency- 13 per cent. In spite of the fact that of serious morphological picture was established in the deceased with acute circulatory insufficiency- the authors find it necessary to apply the following in the patients with acute myocardial infarction: simultaneity in the performance of diagnostic and therapeutic measures; attempt to detect the "signal signs" of the acute circulatory insufficiency as early as possible, and effective treatment with inclusion of new methods, offered by the modern science.

Acute Disease