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Biomedical subjects

M Tsurumi

Publications and source records attributed to M Tsurumi.

12 recordsLinked to original sources

Mitochondrial sequence variation in Carlos capensis (Neumann), a parasite of seabirds, collected on Torishima Island in Japan.

Partial mitochondrial 16S ribosomal ribonucleic acid gene sequences in the ticks Carios capensis collected from black-footed albatross. Diomedea nigripes, colonies on Torishima Island, Japan (30 degrees 28'N, 140 degrees 18'E), were examined. The sequence was compared with those of C. capensis from Hawaii, South Carolina, and Texas. The sequences were all identical in ticks from Torishima and 2 from Hawaii. There were 2-3 transitions between the other Hawaiian and Texas ticks and Torishima specimens. Two transitions were also observed when compared with the ticks from South Carolina. The results suggest the possibility of gene flow between tick populations at each of the 2 geographic sites, which probably was accomplished by tick-infested migratory seabirds at their breeding sites. Sequence comparison analysis indicated that the C. capensis ticks are on the branch with C. marginatus and C. mexicanus ticks and not with Ornithodoros. This supports the revision suggested by Klompen and Oliver (1993).

Animals↗

Pancreatic juice output after pancreatoduodenectomy in relation to pancreatic consistency, duct size, and leakage.

BACKGROUND: A soft pancreas with a main pancreatic duct (MPD) with normal diameter has been considered a high risk for pancreatic anastomotic leakage because of a relatively high output of pancreatic juice, but data are lacking. METHODS: An attempt was made to assess the relationship between the consistency of the pancreas, MPD diameter, pancreatic juice output, and pancreatic leakage after partial pancreatoduodenectomy. The pancreatic parenchyma was classified as of soft, intermediate, and hard consistency in 70 consecutive patients undergoing operation (groups 1, 2, and 3, respectively) by one surgeon. The MPD diameter was determined by means of endoscopic pancreatography or abdominal ultrasonography. Pancreatic juice output was measured for 21 days after operation by using a catheter inserted into the MPD. Anastomotic leakage was identified radiologically by using contrast medium. RESULTS: The mean (SD) pancreatic juice output during a period of 10 days (postoperative days 5 to 14) was 1554 (1073) ml in group 1 (n = 29), 1513 (1060) ml in group 2 (n = 13), and 187 (220)ml in group 3 (n = 28) (groups 1 and 2 versus group 3, p < 0.0001). The MPD diameter was 3.0 (1.6) mm in group 1, 5.9 (2.5) mm in group 2, and 6.6 (2.6) mm in group 3 (group 1 versus groups 2 and 3, p = 0.0001). Anastomotic leaks occurred in four (14%) patients in group 1, three (23%) in group 2, and none in group 3 (p < 0.05). CONCLUSIONS: Patients with a pancreatic parenchyma with an intermediate or normal consistency produced more pancreatic juice and had a higher leak rate.

Adult↗

A proposal mechanism of early delayed gastric emptying after pylorus preserving pancreatoduodenectomy.

To identify the cause of early delayed gastric emptying after pylorus preserving pancreatoduodenectomy (PPPD), we evaluated patients following PPPD and other upper gastrointestinal surgery. An acetaminophen assay was used to objectively evaluate gastric emptying. We observed transient delayed gastric emptying after PPPD in the early postoperative period. This was recognized not only in patients after PPPD but also in patients after standard pancreatoduodenectomy (STPD). The gastric emptying pattern was different between patients with partial gastrectomy and patients with STPD, despite similar reconstructions of gastroenterostomy (Billroth I type reconstruction). There was no early delayed gastric emptying in patients with Billroth II type reconstruction after PPPD or in those with preservation of the vagus nerves after cholecystectomy or transabdominal esophageal transection. We speculate that the anatomic position, namely, a transient torsion or angulation of the reconstructed alimentary tract is the main cause of early delayed gastric emptying after pancreatoduodenectomy.

Acetaminophen↗

[A case report: multiple liver metastasis from gastric cancer responding to intraarterial infusion of sequential low-dose MTX and 5-FU].

A 75-year-old man with gastric cancer having multiple liver metastases was given intraarterial infusion therapy with sequential low-dose MTX (30 mg/body) and 5-FU (1,000 mg/body) for metastatic liver tumors one month after the primary gastric tumor was resected. This therapy was given once a week on admission and every two weeks while an outpatient. A total of 18 courses of this therapy produced marked regression and necrosis of liver metastases. The effect was thus rated as partial response. This patient survived 15 months after surgery. These results indicate that intraarterial infusion therapy with sequential low-dose MTX and 5-FU may be effective in multiple liver metastasis from gastric cancer.

Aged↗

[A study of complications of hepatic arterial infusion catheter].

We studied complications of the infusion catheter, which were implanted in the hepatic artery under laparotomy, and then connected with an implantable infuser port in patients with hepatocellular carcinoma (n = 32) and metastatic liver tumor (n = 11). Infuse-A-Port catheter was used for 31 cases (A group), and Anthron P-U catheter for 12 cases (B group). In B group, the cannulation method was changed; the catheter was placed in the hepatic artery via the gastroduodenal artery, which was ligated and cut to prevent kinks in the catheter. In the A group, 17 cases (54.8%) showed complications such as dislocation of the catheter tip (7 cases) including penetrating duodenal ulcer (2 cases), arterial occlusion (6 cases), injury of catheter (2 cases) and occlusion of the infuser port (2 cases). One case, however, having a fistula between the hepatic artery and the duodenum, died of sudden massive bleeding. In the B group, 3 cases (25.0%) showed complications such as dislocation of the catheter tip (1 case) and arterial occlusion (2 cases). The catheter in B group lasted longer than that in A group. Thus, our cannulation technique using Anthron P-U catheter may decrease the catheter complications.

Catheters, Indwelling↗

[Temporary restoration using light-cured resin].

In spite of various problems involved in chemically cured resin (self-curing resin), e.g., irritability, and heat and shrinkage at polymerization, it has traditionally been the material of choice in the production of temporary restorations. However, light-cured resin, which does not have the disadvantages of chemically cured resin, has recently been developed and applied to clinical treatment. The present study was conducted to examine the clinical application of light-cured resin to temporary crowns. Two types of light-cured resin and one type of chemically cured resin were examined for their mechanical properties. The properties involved in handling and setting, and the methods of producing crowns were also studied. The results were as follows: 1) In the tensile strength test, there was no significant difference between the two types of light-cured resin, i.e., Triad and Unifast LC. The tensile strength of Unifast, a chemically cured resin, was slightly greater than the others, the difference being significant. 2) The Vickers hardness test showed no significant differences between the three types of resin. 3) The mechanical properties of Triad were not influenced by differences in the curing unit (the unit for general oral use or exclusive use) used for polymerization. 4) The test of setting properties revealed that Unifast LC needed longer than Unifast from the 2nd through the 4th clinical stage. In particular, Unifast LC required about 2.5 times the duration needed by Unifast at the 2nd stage in the tray method. 5) The heat generation test showed that the exothermic temperature in Unifast was significantly higher than in the two types of light-cured resin. 6) Heat generation associated with light curing was noted during the use of a light-curing unit for oral use.

Dental Restoration, Temporary↗