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Biomedical subjects

M Tudose

Publications and source records attributed to M Tudose.

8 recordsLinked to original sources
PubMed1997

The combined value of chemoprophylaxis and pneumococcal vaccine in the prevention of recurrent pneumococcal meningitis.

We report the case of an immunocompetent patient who has been the subject of 39 episodes of recurrent pneumococcal meningitis over a 20 year period. The recurrences of bacterial meningitis due to cerebrospinal fluid leakage and the presence of chronic sinusitis were not influenced by the surgical repair of a fistula and the repeated surgical draining interventions on suppurating chronic sinusital foci. Phenoxymethylpenicillin treatment reduced the number of recurrences and the combination of pneumococcal vaccine and penicillin prophylaxis allowed a 5 year period free of any recurrences.

Adolescent↗
PubMed1975

Medium-long incubation posttransfusional hepatitis (a possible immunological implication).

Icteric hepatitis which developed in the first 6 months after blood transfusion was studied in 159 cases. One fourth of these (39) occurred within a period of only 15 days: between the 30th and 45th day after transfusion. So, their incubation period was longer than that of short incubation hepatitis (type A), and shorter than that of long incubation hepatitis (type B). In these cases the incidence of HBs antibodies was more than 10 times greater than in hepatitis with long incubation, and the incidence of HBs antigen was approximately the same as in the healthy control group. This fact suggests the involvement of a special factor in their appearance, probably an immunologic (or of other nature) process giving rise to antigen-antibody complexes in the HB ag-ab system.

Antibodies↗
PubMedDate not supplied

[Acute diffuse peritonitis of a rare cause].

The authors report a rare case of acute onset of non-Hodgkin lymphoma with diffuse peritonitis due to bowel perforation of secondary jejunal involvement. The admission diagnosis in the 18-years-old male with acute abdominal pain for 4 days, guarding on physical examination and pneumoperitoneum on abdominal ultrasonography was peptic ulcus perforation. The palpable splenomegaly and cervical lymph nodes on ultrasonography examination might have raised suspicion of lymphoma. Surgical exploration revealed the peritonitis origin--jejunal perforation, proximal to a stenosing tumor, a gastric tumor and confirmed the splenomegaly. Small bowel resection--end to end anastomosis--and gastric tumor biopsies were performed. The pathological diagnosis was diffuse large B-cell non-Hodgkin lymphoma. Some therapeutic considerations on digestive tract secondary lymphoma are made.

Acute Disease↗