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Biomedical subjects

M U Shaikh

Publications and source records attributed to M U Shaikh.

4 recordsLinked to original sources

Transabdominal gastro-oesophageal devascularization and oesophageal transection for bleeding oesophageal varices.

Fifty consecutive unselected patients presenting with acute haematemesis and melaena from endoscopically confirmed bleeding oesophageal varices were treated by one-stage transabdominal oesophageal transection with gastro-oesophageal devascularization and splenectomy. According to Child's classification, 15 were Grade A, 29 Grade B and six Grade C. The mortality rate was 10 per cent. Postoperative complications included gastric fundal leak (4 per cent), pleural effusion (4 per cent), subphrenic abscess (2 per cent), atelectasis (2 per cent) and pneumothorax (2 per cent). Although five patients (10 per cent) complained of transient dysphagia during follow-up, only one (2 per cent) presented evidence of stricture at the site of oesophageal transection. Clinical encephalopathy was not present in the surviving patients in the postoperative period. No recurrence of bleeding has been recorded in the surviving patients over a follow-up period of 2-3 years.

Adult↗

Appendicitis and schistosomiasis.

A retrospective clinical and pathological study of 15 cases associated with schistosomiasis drawn from 1920 patients undergoing appendicectomy is discussed. The average age of the patients was 31.6 years with a 12:3 male predominance. Hepatomegaly, past or present jaundice, or splenomegaly were not observed. One patient had a previous history of similar right lower quadrant pain for several days. Eighty per cent of the cases showed an inflammatory reaction on pathological examination. In the remaining 20 per cent no inflammation was seen, but there was severe congestion mainly involving the subserosal blood vessels. Schistosoma haematobium was present in 80 per cent of the cases.

Animals↗

Histiocytosis X of the thyroid masquerading as thyroid carcinoma.

The case of a 28-year-old woman with histiocytosis X confined to the thyroid is described. A partial thyroidectomy specimen from this patient was at first interpreted as showing poorly differentiated thyroid carcinoma. Subsequent investigations, including electron microscopy, revealed the true nature of the lesion. Even on retrospective examination, the two conditions can simulate each other very closely and may be easily confused.

Adult↗