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Biomedical subjects

M Ulstein

Publications and source records attributed to M Ulstein.

At least 73 records · Page 4Linked to original sources

Comparison of cytological 'jet-wash' specimens and histology in endometrial carcinoma.

Jet-washing of the uterine cavity for cytological examination has been performed in 200 patients. The results were compared with the histological diagnoses obtained by curettage. In 24 patients with endometrial carcinoma, both methods showed one specimen to be 'not adequate' while the other showed malignancy. A combination of jet-wash and curettage gave a diagnosis in 96% of patients while curettage alone gave a diagnosis in 82%, and cytology alone in 90%. The method is simple and may be of special value in postmenopausal patients.

Curettage↗

Breech delivery.

Perinatal mortality in 700 cases of breech delivery was studied retrospectively and results were compared with those of controls. Cases were matched with those of cephalic presentation for maternal age and parity, foetal gestational age, and birthweight. The perinatal mortality was more than twice as high in the breech group. The difference remained significant after intrauterine foetal death and malformations were excluded. Neonatal death was most frequently caused by the respiratory distress syndrome and prematurity, and in the breech group also by intracranial haemorrhage. The difference in perinatal mortality was more pronounced in the low weight and low gestational age groups. At term the differences in mortality between the two groups were small. Neonatal distress assessed as low Apgar score and the need for special care was far more frequent for the breech group. Special care in premature breech deliveries and a liberal use of caesarean section in recommended. Delivery before the 36th week of gestation should be performed by caesarean section.

Adolescent↗

Plasma estriol, progesterone, cortisol, placental lactogen and alpha-fetoprotein in a pregnancy with an anencephalic fetus followed from the seventh week till term.

Concentrations of total estriol, progesterone, cortisol, human placental lactogen and alpha-fetoprotein were measured in maternal venous plasma at regular intervals from the seventh week of pregnancy until term in a woman with an anencephalic fetus. Except for the first trimester, during which the values were in the lower normal range, the concentration of estriol was constantly subnormal. The "physiological" rise in cortisol levels was absent. Progesterone and HPL were both within the low normal range. The levels of alpha-fetoprotein were transiently raised during the 13th--25th weeks of pregnancy.

Adult↗

Fetal growth retardation associated with inadequate haemodilution in otherwise uncomplicated pregnancy.

The Hb level during pregnancy was followed in 113 non-anaemic women with uncomplicated pregnancy and birth weight of the baby above the 2.5th percentile. There was an inverse correlation close to statistical significance between the birth weight of the baby and the lowest Hb level reached during pregnancy as well as the Hb level in late pregnancy (38th week). A group of seven non-anaemic women with birth weight of the baby below the 2.5th percentile had a significantly higher (p less than 0.001) Hb level in late pregnancy than the normal group. Four of these cases had a statistically significant higher Hb level already in the second trimester. Trends in the reproductive history, complaints in the present pregnancy as well as results of hormone assays and the condition of the baby indicated that the seven cases represented a pathological group with fetal growth retardation. None of the women in the two groups were treated with diuretics. All had iron supplementation in high doses.

Adult↗

Ultrastructural studies on the formation of myoflilaments and myofibrils in the human embryonic and adult hypertrophied heart.

The myofibrillogenesis in the human embryonic heart is described. The synthesis of thin filaments, which are the first to appear, takes place in close proximity to smooth surfaced SR tubules. Z-band material is closely related to the thin filaments and appears first as irregularly distributed patches in the filamenteous mass. Further cellular differentiation includes an organization of the thin filaments/Z-band material. The synthesis of thick filaments, which follows that of the thin filaments, takes place in ribosome rich areas of the cell. They are rapidly incorporated into the strings of organized thin filaments/Z-band material. The periodic binding sites on both kinds of filaments are believed to play an important role in the precise ordering of the filaments. The formation of myofilaments in the adult hypertrophied human heart is also described. The similarities between this process and that observed in the embryonic heart are striking, and we believe it to be the same process.

Adult↗

Primary 9 + 0 cilia in the embryonic and the adult human heart.

Primary 9 + 0 cilia have been found in the embryonic and the adult human heart. Proximally the cilia show the typical 9 + 0 filament arrangement. Rearrangement of the filaments occur in their distal regions. The cilia are usually found in deep invaginations of the cell membrane, but can also be found in a superficial position. Close connections are frequently found between cilia and thin cytoplasmic extensions from neighbouring cells.

Adult↗

Improved staining method for differentiating immature germ cells from white blood cells in human seminal fluid.

A new staining method for differentiating WBCs from immature germ cells in seminal fluid has been studied. It is a combination of Bryan's sperm stain, which particulary stains the acrosomal cap of the spermatozoa and the spermatid, and Leishman's blood stain which stains the WBCs in the same way as found in blood smears. The peroxidase positive granules in the cytoplasm of the PMN leukocytes are seen clearly. Thus, it is possible to differentiate PMN leukocytes from non-separated spermatids when they are present in a common cytoplasm. The staining of acrosomal cap permits differentiation between spermatids and lymphocytes.

Cell Differentiation↗