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Biomedical subjects

M V Antonov

Publications and source records attributed to M V Antonov.

4 recordsLinked to original sources

[Primary heart neoplasms].

The work analyses the anatomomorphological characteristics of primary tumors of the heart in 106 patients; in 101 patients the tumor was benign (myxoma, neurinoma, rhabdomyoma) and in 5 malignant (angiosarcoma, liposarcoma). Surgical treatment was conducted in 99 patients; hospital lethality was 7.1%. Six patients who refused an operation died at other therapeutic institutions, one patient died on admission to the clinic from occlusion of the left atrioventricular orifice by the tumor. It is pointed out that the diversity and the various degree of the clinical manifestations of the disease are predetermined by the localization and morphological characteristics of the new growths, their size, and mobility. The authors emphasize that knowledge of the anatomomorphological features of primary tumors of the heart and their early diagnosis are conducive to a differential approach in each concrete situation and to the choice of the optimal volume of an urgent surgical intervention.

Adolescent↗

[Familial myxomas of the heart].

An analysis has been made of the clinical, diagnostic, surgical and morphological aspects of familial cardiac myxomas, potentialities of their intravital diagnosis and prevention. No morphological differences were established between familial and sporadic cases of cardiac myxoma.

Adolescent↗

[The clinico-morphological characteristics of psoriatic nephropathy].

Based on studying the data obtained during examination of patients with psoriasis combined with the urinary syndrome possible varieties of psoriatic nephropathy, namely chronic glomerulonephritis (CGN) and amyloidosis were distinguished. CGN combined with psoriasis was mainly represented by latent glomerulonephritis (GN) and morphologically, it was mostly represented by the mesangio-proliferative variant, with IgA and C3 being fixed on the basal membrane of the capillaries and in the mesangium. The clinicomorphological feature of that form of psoriatic GN is combination of the signs of both associated CGN and hyperuricemia and IgA-nephritis. Special emphasis is laid on the diagnosis of rapid-progressing GN which is of paramount importance for institution of early etiopathogenetic therapy. Amyloidosis associated with psoriasis is characterized by the signs of acquired disease (AA-amyloidosis) and does not differ in its course from amyloidosis coupled with other diseases.

Adolescent↗

[The morphological characteristics of psoriatic nephropathy].

Three variants of psoriatic nephropathy are distinguished on the basis of light microscopical and immunohistochemical study of 23 cases/20 kidney biopsies and 3 autopsy cases/: glomerulonephritis, amyloidosis and minimal kidney alterations. Chronic glomerulonephritis is mainly of a mesangioproliferative type with fixation of IgA and C3 on the mesangium and basal membranes of glomerular capillaries. Psoriatic amyloidosis has morphologically, all the features of acquired amyloidosis/AA-amyloidosis/. Thus psoriatic nephropathy is a reflection of a disturbed homeostasis.

Adolescent↗