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M V Golovanov

Publications and source records attributed to M V Golovanov.

14 recordsLinked to original sources
PubMed1981

[Dynamics of changes in halo-forming cells during pathologic processes].

The method of detecting halo-forming cells (HFC) in the peripheral blood is described and the data characterizing the time course of changes in their number are presented. These data indicate that the process of halo formation is not based on the immunological components of plaque formation (complement, antigens or hemolyzing antibodies). HFC have been shown to appear in the peripheral blood somewhat earlier than cells capable of producing antibodies, i.e. plaque-forming cells.

Animals↗
PubMed1980

[Pseudoplaque formation in immunologic reactions].

It has been proved by diverse experimental methods that cell suspension prepared from the immunocompetent organs and tissues by Jerne's method modified by N. N. Klemparskaya presents a hypertonic medium stimulating formation of false plaques. This evidence suggests that immune-like plaques (aureola) may be formed in the absence of antigen rather than due to lysis of red cells or destruction of plaque-forming cells.

Animals↗
PubMed1975

[The effect of hormones regulating calcium metabolism on the growth and metastasis of experimental tumors].

Injection of parathormone and thyrocalcitonin into rats with DMBA induced sarcomas resulted in a considerable stimulation of the metastasization process. It was found that the level of total Ca++ in tumor tissue was reduced under the influence of PTH. Under conditions of chronic exogenous hyperparathyroidism autoimmunereactions were suppressed. A prolonged administration of TCT did not alter considerable the total Ca++ content in tumor and markedly activated the autoantibody production in immunocompetent cells.

Animals↗
PubMedDate not supplied

[Permeabilization of tumor cells induced by pulsed electric fields in vitro].

The permeabilization of tumor cells in vitro under the action of pulsed electric fields with a duration of 6 mks in the range of amplitudes 1-7 kV/cm was studied. In the mode of excitation in the ambience of localized plasma discharge in a chamber of special design, an enhanced damage to cells in suspension was observed. It is assumed that the enhancement is due to the synchronous action of the electric field and acoustic shock wave pulses. In the mode without the plasma breakdown of ambience, when the pulse duration of electric field of intensity of 1-2 kV/cm was increased to 60 mks, the efficiency of permeabilization increases nearly by one order. The experimental results are compared with the known theoretical models of cell membrane electroporation.

Acoustics↗