Fatal infectious mononucleosis. Report of a case with a review of the literature.
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Biomedical subjects
Publications and source records attributed to M Várbiró.
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In 10 cases of hairy cell leukaemia histological, cytological, cytochemical and in some of the cases immunocytological investigations were carried out. In addition to clinical, cytological and cytochemical findings arising suspicion of hairy cell leukaemia, in three cases the multifocal reaction of acid-phosphatase appeared to be tartarate sensitive (at the concentration of L+-tartaric acid--0,75%), indicating in accordance with findings of Burns et al. (9), that tartarate resistency of the acid-phosphatase reaction ("isoenzyme 5" Katayama és mtsai, 24) has no absolute diagnostic significance. Pathomorphological investigation of different tissues (spleen, lymph node, bone marrow, liver) has revealed the characteristic localization of the spleen infiltrates (cords of Billroth) and the formation of the so called pseudosinuses. These morphological findings may contribute to the diagnosis of hairy cell leukaemia.
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In the first year of its existence the Malignant Lymphoma Reference Centre in Hungary diagnosed 383 new cases, which may represent about half the cases occurring in this country. The distribution of the cases was as follows: Hodgkin's disease 69 (18%); non-Hodgkin's malignant lymphoma 290 (75.7%), unclassifiable 12 (3.2%), hairy cell leukaemia 4 (1%), Lennert's lymphoma 8 cases (2.1%). Some features of the distribution of malignant lymphomas are discussed.