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Biomedical subjects

M Vázquez-Botet

Publications and source records attributed to M Vázquez-Botet.

6 recordsLinked to original sources
PubMed1997

Neonatal lupus erythematosus.

This is a case of an infant with neonatal lupus erythematosus who presented the characteristic cutaneous lesions without evidence of systemic involvement. NLE is a rare condition which affects newborn infants from mothers who may me asymptomatic or have a connective tissue disease, with or without autoantibodies to extractable nuclear antigens Ro (SS-A), LA (SS-B) or ribonucleoproteins. The skin lesions are usually annular in configuration and resemble those of subacute cutaneous lupus erythematosus. Congenital complete heart block (CHB) may be present in addition to the cutaneous lesions. This is a review of NLE focusing on its clinical manifestations, serologic markers, pathogenesis and treatment.

Female↗
PubMed1994

Pigmented macules on palms and soles in Puerto Ricans.

BACKGROUND: One-third of melanomas in Puerto Ricans occur on the skin of palms and soles. This is a study to define the characteristics of melanocytic nevi in those locations. METHODS: A sample of 1,039 patients were randomly examined for pigmented macules on the palms and soles. After informed consent, biopsies of these lesions were done on 67 patients. RESULTS: Among the patients, 13% were found to have pigmented macules on the palms and soles. Volar melanocytic macule was the most frequent lesion. CONCLUSIONS: Melanocytic nevi occur frequently on volar skin. The criteria for removal of these lesions should not be different from those lesions at other locations.

Adolescent↗
PubMed1993

Epidemiological study of tinea capitis in Puerto Rico.

Two separate studies were carried out to determine the dermatophytes responsible for tinea capitis in Puerto Rico. A retrospective study to determine those agents during the period between 1979 and 1989 revealed a total of 36 mycologically positive cases. The causative organisms consisted of the following species: M. canis, 14 cases (38.9%); T. mentagrophytes, 7 cases (19.4%); T. rubrum, 7 cases (19.4%); M. gypseum, 5 cases (13.9%); and T. tonsurans, T. verrucosum, unclassified Microsporum species, 1 case each (2.8% each). In a prospective study, fungal cultures were obtained from the scalps of 95 randomly selected children (45 males, 50 females) seen at the outpatient dermatology clinics of the Medical Sciences Campus of the University of Puerto Rico for a variety of skin problems but with no symptoms or signs of disease. One culture was positive for M. canis. All other cultures were negative. The significance of these findings is discussed as well as their relation to the incidence of T. tonsurans scalp infections in the Unites States.

Adolescent↗
PubMed1990

[Malignant melanoma in Puerto Rico].

An epidemiological study of malignant melanoma in Puerto Rico was done by reviewing the Puerto Rico Cancer Registry for all melanoma cases reported between the years 1981 to 1987. A total of 367 new cases were documented with the annual incidence ranging from 1.20 to 2.12 per 100,000 inhabitants with a mean of 1.59. Most of the patients were between 40 and 80 years of age with a peak in the sixties. Nearly one half of the tumors were located on the extremities, most notably on the feet, sharing this predilection with Blacks and Japanese. The most frequently recognized clinico-histologic type was the superficial spreading melanoma followed by the acral lentiginous, the nodular and the lentigo maligna melanoma. Nearly one third of the total cases were not classified according to the histologic type, while Clark's levels and Breslow's thickness were not reported in 44 and 84% of the cases, respectively. When compared to a previous study during 1977 to 1980, the average annual incidence of new cases increased from 0.92 to 1.59 per 100,000 documenting an increased incidence of the condition in our population, but not as significant as that registered in the United States.

Adolescent↗