Biomedical subjects

M Véron

Publications and source records attributed to M Véron.

130 records · Page 8Linked to original sources

PubMedDate not supplied

[A proposal for Salmonella nomenclature].

A single species, composed of six subspecies, was found in the genus Salmonella following a numerical taxonomy and a study of the DNA relatedness (see p. 223, Le Minor et al.). The Salmonella nomenclature is herein updated to take into account modern taxonomic knowledge. The single Salmonella species is S. choleraesuis (type species). Six subspecies are proposed: (1) S. choleraesuis subsp. choleraesuis subsp. nov. is composed of all Salmonella strains formerly assigned to the subgenus I; (2) S. choleraesuis subsp. salamae subsp. nov. corresponds to the former subgenus II; (3) S. choleraesuis subsp. arizonae comb. nov. is composed of monophasic serovars of the former subgenus III ("Arizona"); (4) S. choleraesuis subsp. diarizonae subsp. nov. is composed of diphasic serovars of the former subgenus III ("Arizona"); (5) S. choleraesuis subsp. houtenae subsp. nov. corresponds to the former subgenus IV; and (6) S. choleraesuis subsp. bongori subsp. nov. is composed of strains positive for dulcitol fermentation, ONPG, and KCN tests. Type strains are proposed for each subspecies. The name of S. choleraesuis subsp. choleraesuis serotypes (e.g. typhimurium) should be used without italicization or underlining (e.g. S. choleraeusis subsp. choleraesuis ser. typhimurium). A practical and unofficial use of non-italicized serotype names is discussed.

Salmonella↗

PubMedDate not supplied

[A method to select diagnostic criteria from Bayes' theorem and information theory (author's transl)].

An algorithm is proposed to order a list of characteristics according to their efficiency for diagnosis. Two diagnostic ability coefficients (DAC), INF and TAX, are described. The calculus of INF coefficient is based on Bayes' theorem, using the occurrence of various diagnosis, and on information theory. TAX coefficient is a linear approach of the former. Both coefficients are tested with the study of 1891 strains of Enterobacteriaceae, originating from urines. The results are compared with those given by Gyllenberg's separation and characterization figures. Theoretical examples are also provided for computing purposes.

Enterobacteriaceae↗

PubMedDate not supplied

[An acellular vaccine from "Pseudomonas aeruginosa." I. Preparation and activity (author's transl)].

From a strain (72 V) of Pseudomonas aeruginosa, we have prepared an acellular vaccine P2, which showed a good efficiency against homologous experimental infection in mice. The extraction procedure is as follows: washed bacterial cells are suspended in 0,15 M NaCl and heated at 60 degrees centigrade for 1 hr; after centrifugation, the supernatant fluid is precipitated with one and five volumes of ethanol. This acellular vaccine possess the following properties: rapid efficiency (10 days) after a single or three inoculations of very small doses (ED50 = 0.014 mug per mouse); weak toxicity (LD50 = 1,148 mug per mouse, subcutaneous route); capacity for production of specific protective antibodies.

Animals↗

PubMedDate not supplied

An acellular vaccine from Pseudomonas aeruginosa: homologous and crossed protection between serogroups according to Habs' classification.

Homologous and cross-reactions were studied in 16 strains of Pseudomonas aeruginosa belonging to different O serogroups according to Habs' classification. By slide agglutination, cross-reactions were rare between the strains of two or three serogroups: O2, O5 and O16; O1 and O9; O7 and O8; O13 and O14. Experiments of cross-protection have been performed in mice inoculated with acellular vaccines prepared from the 16 studied strains. A high homologous protection was observed with all the 16 strains, which is in favour of existence of an O serogroup-specific immunity. However, it exists some cross-protective reactions between the serogroups. This cross-protection allows to reduce the numbers of strains for a polyvalent vaccine. A classification of P. aeruginosa into 8 classes of related serogroups (A to H) is proposed which could be a basis for an antigenic classification of P. aeruginosa.

Agglutination Tests↗