[Depressive pseudodementia: clinico-therapeutical implications].
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Brain↗
Biomedical subjects
M Vega Piñero
Publications and source records attributed to M Vega Piñero.
[Progress and therapeutic response in the obsessive-compulsive disorder].
The purpose of the present work was to analyze the outcome of patients diagnosed of Obsessive Compulsive Disorder (OCD) after Hospital discharge from our Unit, focusing on therapeutical efficacy immediately after discharge and in the follow up, searching for good evolution predictors. We have studied 42 patients (26 females and 16 males) diagnosed of OCD according to ICD-9 diagnostic criteria, all patients were hospitalized during a seven years period 1981 and 1988. Therapeutical response was evaluated through a (1-4 punctuation) of a Clinical Global Impression Scale considering the changes from the moment the patient was hospitalized, the day of discharge and in the follow up (mean 4.1 years). 73.8% and 71.4% were considered as treatment "responders" the day discharged and in the follow up respectively. Through a multiple logistic regression, treatment with serotonergic drugs and insidious onset of the illness were identified as short-term treatment response predictors, while the absence of a previous obsessive personality was a long-term therapeutical response predictor. Our results show the efficacy of serotonergic drugs and the tact that the presence of a previous obsessive personality could have a prognostic value in OCD.
Adolescent↗
[Psychopharmacologic treatment of bulimia nervosa].
Since the inclusion of Bulimia Nervosa (BN) in DSM-III as a nosological entity, it has been a focus of attention in the literature. To the present day several therapeutical approaches have been developed, pharmacological, psychological either separated or combined with diverse results. We have studied 20 patients diagnosed of BN according to DSM-III-R diagnostic criteria, from a psychopathological, and evolution point of view, the therapeutical response to a fixed daily dose of Fluoxetine 80 mg., during three months, with evaluations on days: 0-14-30-90. The mean age of the sample was 19.5 years; in 70% at the onset of the illness the Anorexia Nervosa symptomatology was prominent; there was a predominance of affective-obsessive previous personality traits in 60%, 100% showed unsatisfied or altered body image. We want to point out the quick improvement of various parameters such as: the constant eating desire, the binge eating episodes, the vomiting, the misuse of laxatives and the affective and anxious symptomatology. We compare our results with previous studies and make a review of the literature on this topic, we also give an efficacy profile of the different psychopharmacological drugs used in the treatment of eating disorders and a clinical guide to identify those patients who could improve with a psychopharmacological treatment.
Adolescent↗
[A prospective study of patient with schizophreniform disorder: a nosological dilemma?].
We study retrospectively 42 inpatients of the psychiatry department of the Ramón y Cajal Hospital, through a period between 1st January of 1988 and the 31st December 1993. All of them were diagnosed at discharge of schizophreniform disorder according to DSM-III R diagnostic criteria and it was in all of them the index episode of the psychosis. Sociodemographic, clinical, evolutive, and therapeutical variables are analyzed. We made a new assessment of the patients in the sample during April 1994 through a direct interview. The mean follow-up period was 4.18 years. The main results were: A predominance of male/female proportion (2/1), nearly half of the sample had emotional or psychosocial stressors previous to the episode. Previous schizoid personality traits were found in 57.1%. 11.9% had first degree relatives antecedents of schizophrenia and 19% of non-bipolar affective disorders. At follow-up 40.4% needed to be hospitalized again. It is noteworthy that 80.9% were rediagnosed during follow-up as schizophrenia.
Adult↗