[Acute/subacute nonpurulent Quervain's thyroiditis].
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Biomedical subjects
Publications and source records attributed to M Ventz.
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Gynaecomasty is no disease sui generis, but a symptom which may underlie different causes. Steroidal substances, above all oestrogens play a dominating role in these cases. Diagnostic and therapeutic measures must comply with the known causal factors. The gynaecomasty during puberty exhibits a high spontaneous retrogression rate. Only seldom an operative correction becomes necessary.
This paper deals with the activity of glucose-6-phosphate dehydrogenase in patients with hyper- and hypothyroidism as well as in hyperthyroxinaemic rats. The activity of glucose-6-phosphate dehydrogenase is enhanced in red blood cells of hyperthyreotic patients and hyperthyroxinaemic animals. The activity will be decreased to normal range in patients by administration of antithyreotic drugs, such as thiamazole. Patients with hypothyroidism exhibit decreased enzymatic activity. It is suggested that thyroid hormones stimulate the HMP-shunt in red blood cells as a defence mechanism against additional oxidative stress.
It is reported on the behaviour of the fasting serum levels of the free fatty acids and the free glycerol in patients with hyper- and hypothyroidism. The two parameters were significantly increased in hyperfunction of the thyroid gland, whereas a decrease was found in hypofunction. The possible causes are discussed with the help of literature.
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It is reported on in vitro tests of the thyroid gland in 7 males with normal weight and 9 adipose ones. No clear difference was found in the two groups. The TSH level, too, after TRH stimulation is not significantly different so that a latent primary hypothyroidism cannot be ascertained.