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M Vetner

Publications and source records attributed to M Vetner.

At least 37 records · Page 2Linked to original sources

A case of massive, unilateral oedema of the ovary simulating tumour.

This paper describes the first reported Scandinavian case of massive unilateral oedema of the ovary. It represents the tenth such case in the literature. The probable pathogenesis is partial torsion of the mes-ovarium. If suspected clinically, such ovaries might be conserved.

Adolescent

Gastric carcinoma I. The reproducibility of a histogenetic classification proposed by Masson, Rember and Mulligan.

The purpose of the present paper has been to examine the reproducibility of the classification of gastric carcinomas, as proposed by Mulligan and Rember. Two microscopic slides from each of one hundred randomly selected specimens of gastric carcinoma, obtained by gastrectomy or gastric resection, were classified independently by both authors. Neither of the authors knew which slides originated from the same specimen. The inter-examiner reproducibility rate was 79 per cent. The reproducibility rates of the diagnoses with two independent slides from the same tumour was 74 per cent with examiner I and 80 per cent with examiner II.

Adenocarcinoma

Gastric carcinoma 2. An analysis of morphological and prognostic parameters correlated to the classification proposed by Masson, Rember and Mulligan.

One-hundred and fifteen gastric adenocarcinomas were classified according to Mulligan and Rember into one of the following types: Intestinal cell carcinoma (IC), pyloro-cardiac gland carcinoma (PC), mucous cell carcinoma (MC) and unclassified. The tumour type was correlated to the growth pattern and inflammatory reaction at the margin of the tumour, invasion of the veins and nerve sheaths, Dukes' stage, intra- and extracellular mucous production, and occurrence of intestinal metaplasia in the non-tumour bearing parts of the gastric mucosa. MC was the only type of tumour producing the macroscopic picture "linitis plastica". PC was the type of tumour that dominated in the cardiac region. The following parameters showed no relation to tumour type: Sex and age, size of tumour, invasion of lymphatic vessels. This study suggests that the three types of tumour are different entities, MC being the most aggressive and IC the least aggressive of the types of tumour.

Adenocarcinoma

Polyvinylpyrrolidone-storage disease. Light microscopical, ultrastructural and chemical verification.

The light and electron microscopical findings in the polyvinylpyrrolidine-storage disease are reported on the basis of biopsies of skin, striated muscle, bone marrow and liver from one patient and a subcutaneous nodule from another patient. Both patients suffer from diabetes insipidus and have been treated for several years with Insipidin retard, which contains polyvinylpyrrolidone (PVP) as the retarding agent. Deposits of PVP have been demonstrated in all the tissues examined and can easily be recognized by certain staining qualities. The combination of haematoxylin-eosin, elastin (Weigert), alkaline Congo red and Sirius red for amyloid and PTAH is specially to be recommended. The ultrastructural findings consist of intracellular vacuoles containing a granular material and probably representing lysosomes. The final identification of the nature of the deposits has been made by spectrophotometric analysis. The suspicion of a case of PVP-storage disease should result in a skin biopsy which usually is sufficient for the diagnosis.

Bone Marrow

Relationship between heart weight and the cross sectional area of the coronary ostia.

Sex variation in the area of the coronary ostia was studied in hearts with a normal weight (heart weight less than 400 g) and hypertrophic hearts (heart weight greater than or equal to 400 g). Also studied was a possible sex difference in the correlation between heart weight and the area of the coronary ostia. The study was performed on 379 post mortem hearts. In the group of hearts with a normal weight the area of the left coronary ostium in both sexes was greater than the right but the difference was statistically insignificant. There was no sex difference in the area of the left coronary ostium, whereas the area of the right coronary ostium was statistically significantly less in women. In the group of hyperthopic hearts the left coronary ostium increased in area with increasing heart weight. The difference in the area of the left coronary ostium between hearts with normal weight and hypertrophic hearts was stastically significant in men, but not in women. The right coronary ostium showed minimal increase in size with increasing heart weight and the difference in both sexes between the two groups was statistically insignificant. In the group of hypertrophic hearts the heart weight was best correlated to the area of the left coronary ostium in both sexes, but the values did not reach statistically significance. On the basis of this study the area of the right coronary ostium appears to be a bottleneck with regard to an adequate blood supply to a hypertrophic myocardium.

Adult

Relationship between length of the left main coronary artery and heart weight.

The length of the left main coronary artery (LMA) was determined in post-mortem, non-fixed hearts of normal weight (heart weight less than 400 g, group I) and hypertrophic hearts (heart weight greater than or equal to 400 g, group II). Hearts from 76 men and 88 women in group I and 136 men and 61 women in group II were studied. The mean length of LMA in group I was 9.1 mm in men and 8.4 mm in women. Corresponding values in group II were 10.3 mm and 8.8 mm. There was no significant sex difference in the length of LMA in group I, but the sex difference in group II was significant (p less than 0.01). The difference in length of LMA between groups I and II reveals that the difference in men was significant ( less than 0.02), but insignificant in women. In the case of both sexes no significant correlation between heart weight and the length of LMA was found either in group I or group II. There was a significant correlation between the area of the left coronary ostium and the length of LMA in men in group I (p less than 0.05), but not in women. Corresponding comparisons of both sexes in group II were statistically insignificant.

Adult

Rytand-Lipsitch syndrome.

An 84-year-old woman had Rytand-Lipsitch syndrome, ie, total atrioventricular block resulting from destruction of the central areas of the conducting system due to extension of calcification from the fibrous ring of the mitral valve. In a postmortem coronary arteriographic study of 500 hearts, degenerative calcification of the fibrous ring of the mitral valve was demonstrated in 4.4% (95% confidence limits--2.8% to 6.6%), rheumatic valvular changes not being included. There were significantly more women than men with calcification of the mitral valve apparatus (P less than .00005). Division of the material into two groups larger than or equal to 70 years and less than 70 years showed a statistically significant sex difference in the former group (P les than .005), whereas the sex difference was of borderline significance in the latter group (.1 greater than P greater than .05).

Aged