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Biomedical subjects

M Vogeleer

Publications and source records attributed to M Vogeleer.

7 recordsLinked to original sources

[The effect of a histamine nasal provocation tests on the results of the tubal compliance manometry test (TCM) in normal study subjects].

The Tubal-compliance-manometric test (TCM) assesses the passive and active tubal opening as well as the equilibration ability. The pressures necessary to open the eustachian tube (ET) are measured while performing the Valsalva maneuver and during swallowing (if needed with added pressure). The equilibration ability is also checked. Subjects with normal tympanometry were twice tested, at an interval of 1 to 2 weeks; 52 ETs (in 28 persons) entered the study. According to a variance analysis (ANOVA), there was no significant difference (alpha = 5%) between the two measurements (the results were time-independent). The mean opening pressures were 610 daPa (SD = 108) during the Valsalva maneuver and 97 daPa (SD = 40) during the swallow test. Nearly 14% of the tubes were considered floppy (unable to maintain a positive pressure). In order to study the influence of mucosal swelling on tubal function, 9 subjects (18 tubes) underwent a TCM before and after a nasal histamine provocation. The opening pressures in both tests were significantly altered (higher) after the provocation (ANOVA; 0.001 less than p less than 0.01). One tube became obstructed and two became floppy. The equilibration ability was not altered. The TCM proved to be of value as an easy, fast and quantitative test for assessing active and passive tubal function.

Acoustic Impedance Tests

Normative multifrequency tympanometric data on otosclerosis.

Acoustic resistance, reactance and phase angle were assessed for the two probe tone frequencies (220 and 660 Hz) on 29 otosclerotic middle-ear systems under accurately defined experimental conditions. Only otosclerotics with normal tympanic membranes were accepted in this statistical survey. The main purpose of these measurements was to provide numerical data for middle-ear modelling. If nevertheless a diagnostic parameter is sought from these data, the immittance values can be compared with data obtained on 30 normals under identical experimental conditions. The phase angle at 660 Hz seems the best choice, but the discrimination power is still poor.

Acoustic Impedance Tests

A tympanometric approach to otosclerosis.

A formula has been elaborated to estimate the resonance frequency of the middle ear from non-simultaneously recorded susceptance and conductance tympanograms at 220 and 660 Hz. The formula is tested on 30 normal and 29 otosclerotic ears. From these experimental results one can conclude that the middle-ear model (proposed by Lutman), from which the formula was deduced, is too crude to assess the resonance frequency. Nevertheless a ratio of phase angles functions at 220 and 660 Hz, introduced in that formula, is always qualitatively linked to the resonance frequency. Experimental data proved that this ratio can be used to distinguish tympanograms from otosclerotic ears with normal tympanic membrane from those obtained from normals. A statistical treatment is proposed to estimate the probability of false-positive or false-negative cases as a function of the value of that ratio.

Acoustic Impedance Tests

[A comparative study of 2 tests for auditory tube function and their effects on swimming].

We studied a group of adults and a group of children. All the test subjects were member of the swimming club and were subjected to an intensive training program for competition swimming. Two easy to perform Eustachian tube tests were compared, i.e. the Bluestone 9 steps test (tympanometry) and the measurement of the opening pressure with a pressure transducer during Valsalva and swallowing. We discuss the advantages and disadvantages of each test and the influence of swimming on the Eustachian tube function in adults and children.

Acoustic Impedance Tests

[Frequency analysis of the various stimuli used in brain stem electric response].

It was our aim to analyse the frequency spectra of these different stimuli in order to select the most suitable stimulus as one wants to apply BER either as objective audiometry or as oto-neurological means of diagnosis. The kind of stimulus is important because its characteristics will condition the parameters of the electro-physiological response. As oto-neurological means of diagnosis, it will be preferable to use the shortest possible stimulus and by no means a filtered stimulus. As objective audiometry, a long stimulus will be used with a less rough onset, which thus presents a narrow frequency spectrum and still creates a clear P5/FFP7 complex. For both applications the Logon offers the best compromise.

Audiometry