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Biomedical subjects

M Volant

Publications and source records attributed to M Volant.

2 recordsLinked to original sources

[Cranioplasty using computer-designed implants (preliminary report)].

The co-operation among plastic surgeons and computer experts is presented demonstrating the reconstruction of a cranial bone defect of a patient. The adequacy of manufactured implant for reconstruction of cranial bone defect on the base of classic methods in only approximate. Computer aided design is needed for creating a more sophisticated implant. Cranial CT is digitised and a 3 dimensional model is created. The precise implant, manufactured by a computer directed milling machine, fits ino the bone defect. During the operation the cranial bone defect is explored, the bone edges are identified. The implant is fixed and the skull skin is closed. The authors demonstrate a successful operation of a cranial bone defect of 9 x 6.7 cm, the complicated shape and bone surface was reconstructed by a computer aided and manufactured implant. The co-operation of plastic surgeon and computer experts are essential during the process of implant design. The computer assisted and manufactured implants are suitable for the most sophisticated functional and aesthetic reconstruction of bone defect with complicated surface and irregular pattern.

Adult

Investigation of a valuable biochemical indicator in radiotherapy. III. Serum lactate dehydrogenase enzyme level on irradiation of cancer patients.

In search of a valuable indicator of the effects of radiotherapy, the immune answer, leucocyte number, plasma free hemoglobin and serum haptoglobins were studied [3, 7]. Among the enzymes of interest, lactate dehydrogenase (LDH) was chosen for measurements, as it gave significantly elevated values on irradiation of blood, in vitro [6]. In the present study LDH values are shown on irradiation of cancer patients by differing types of radiation sources during treatment for several weeks. In 63% of the cases increase in respect of the untreated control was observed, and this was manifested during 4 or 5 weeks' treatment. "Modern beams", as high-energy X-ray and electron-ray increased LDH enzyme values less than conventional 200-kV X-rays and 60Co-gamma-rays. In the study of LDH isoenzymes, components 4 and 5 gave elevated values, others remained unchanged. Correlation between LDH enzyme and plasma free hemoglobin was estimated.

Cobalt Radioisotopes