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Biomedical subjects

M Vouge

Publications and source records attributed to M Vouge.

18 recordsLinked to original sources

Multiple sclerosis and corpus callosum atrophy: relationship of MRI findings to clinical data.

Among 110 patients (45 men, 65 women), aged 15 to 66, with clinical and/or biological diagnosis of multiple sclerosis (MS), severe to moderate corpus callosum (CC) atrophy was observed in 67 (60%) patients. Correlation between CC atrophy, brain atrophy, duration and severity of clinical symptoms, and high signal white matter areas, was carried out in 90 patients. Mean age was 46 years for patients with severe CC atrophy, and 33 years for those without atrophy. Mean duration of the disease was 14 years in patients with severe atrophy, and 5 years in patients without atrophy. Severity of clinical symptoms is more pronounced in patients with severe CC atrophy. Numerous or large white matter high signal areas are observed in patients with severe CC atrophy on T2-weighted images. CC atrophy appears earlier than brain atrophy in the course of MS.

Adolescent↗

[Osteonecrosis of the femur head caused by sickle cell anemia in Benin. Epidemiologic and radiologic aspects].

The author reports 19 aseptic necrosis of the femoral head, due to sickle cell anemia, collected in 14 black people native from Benin. Sickle cell anemia is the most frequent etiology of osteonecrosis there. They are generally observed between 10 and 30 years of age. A systematic and complete study of the radiological signs has been carried out. The peculiar severity of the disease in black Africa is related to the chronicity of the sickling disorder, the delay brought to the diagnostic, the lack in therapeutic media.

Adolescent↗

[Osteonecrosis of the femoral head of sickle-cell origin. Apropos of 19 cases observed during a year in Benin. Proposal for radiologic classification].

The author reports 19 aseptic necrosis of the femoral head, due to sickle-cell anemia, collected in 14 black people native from Benin. Sickle-cell anemia is the most frequent etiology of osteonecrosis there. They are generally observed between 10 and 30 years of age. A systematic and complete study of the radiological signs has been carried out. The peculiar severity of the disease in black Africa is related to the chronicity of the sickling disorder, the delay brought to the diagnostic, the lack in therapeutic media. A six stage X-ray classification is argued because of the most severe aspects.

Adolescent↗

[Ultrasonic diagnosis of acute cholecystitis. Critical study of 50 verified cases].

A retrospective study of fifty surgically proven cases of acute cholecystitis and a review of the literature enabled the authors to summarise the sonographic features of the disease. These may include one or several of the following signs: thick gall bladder wall with an occasional posterior hypoechogenic rim, diffuse echogenicity of the purulent bile and local tenderness at the passage of the transducer. If an abscess is present, there is a hypoechogenic area in contact with the gall bladder. The technical problems of the B scan performed on an emergency basis make the use of real time intercostal scans invaluable. Ultrasound should be the first and may be the radiological examination performed in this situation.

Acute Disease↗

[Feasibility of radiological exploration of the main bile ducts for stones (author's transl)].

The results of cholangiography conducted pre-and post operatively (through Tatute), and during choledochotomy on 100 patients for confirmed or suspected bile duct stones are analyzed. Pre-operative opacification of the main bile ducts resulted in 13 p. cent of false positives and in a similar number of false negatives. Results of investigation during operation produced similar errors respectively in 14 and 2p. cent o of cases. Several recommendations are outlined to limit the proportion of unnecessary choledochotomies without increasing the number of neglected stones.

Cholangiography↗

CT findings of atypical forms of phakomatosis.

Three cases with unusual manifestations of phakomatosis are reported. The first two had clinical symptoms of neurofibromatosis but CT disclosed nodular subependymal calcifications as in tuberous sclerosis. The third one presented with cerebral calcifications as found in both tuberous sclerosis and Sturge-Weber syndrome, though he had no clinical symptoms of phakomatosis.

Adult↗

[Roentgenographic features in pigmented villonodular synovitis (concerning a carpal location) (author's transl)].

Pigmented villonodular synovitis is a benign proliferation of the synovial membrane. Its pathogenesis is not well known. It results in an articular swelling without great pain. Its roentgenographic aspect is a combination of an opacity of soft tissue and epiphyseal damages, i.e. cortical erosions and lacunae surrounded by osteosclerosis. Hyperplasty of the synovial membrane is explicited by arthrography and arteriography. The authors report one case of pigmented villonodular synovitis in the carpus: that is an uncommon location of that disease which most often involves the knee.

Adolescent↗