Biomedical subjects

M W Brennan

Publications and source records attributed to M W Brennan.

4 recordsLinked to original sources

PubMed1987

Chronic hematic cyst of the orbit.

A chronic hematic cyst of the orbit caused unilateral globe displacement in four patients, two of whom had a past history of orbital trauma. The onset of a painless vertical displacement of the globe ranged from 3 weeks to 4 years. Computed tomographic (CT) findings demonstrated a homogeneous, nonenhancing, subperiosteal mass in the superior orbit in three patients and the inferior orbit in one. At surgery, all patients had masses surrounded by a pseudocapsule without epithelial or endothelial lining. The history, age distribution, and CT findings help to differentiate this entity from other causes of unilateral exophthalmos.

Adolescent↗

PubMed1985

Magnetic resonance imaging of optic gliomas.

We compared magnetic resonance imaging of the optic nerves and chiasm with computed tomography in four patients (a 17-year-old girl, a 14-year-old boy, a 13-year-old girl, and a 22-year-old woman) with biopsy-proven or suspected optic gliomas. Orbital abnormalities were effectively viewed by both techniques. Gliomatous and normal optic nerves had similar spin-echo magnetic resonance imaging characteristics. Magnetic resonance was superior to contrast-enhanced computed tomography for identification of the intracranial optic nerves, chiasm, and optic tracts, but computed tomography delineated orbital anatomic and spatial relationships better.

Adolescent↗

PubMed1983

Radiation therapy for Graves' disease.

We used radiation therapy (a total of 2,000 rads) to treat 14 patients (three men and 11 women, ranging in age from 27 to 72 years) with Graves' disease. Three of these patients had refused to take corticosteroids and the other 11 had failed to respond to them, had experienced side effects, or had other contraindications to their use. After follow-up periods ranging from six months to three years, soft-tissue inflammation was reduced in 13 of the 14 patients. All but two patients showed a decrease in proptosis of 1 to 3 mm. Myopathy showed the least improvement. Although we noted transient eyelid erythema, there were no permanent sequelae and none of the patients has had a recurrence of the inflammation.

Adult↗

PubMedDate not supplied

Recurrent subtemporal epidural hematoma with second, third and fourth cranial nerve compression.

A patient who was admitted with visual loss and, third and fourth cranial nerve paresis as only evidence of a recurrent epidural hematoma is presented. A review of some of the mechanisms suggested in the literature to explain the etiology of ocular signs in the presence of extracerebral collections is offered. We propose an additional possible mechanism and review the anatomical explanation for the development of these symptoms.

Adult↗