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Biomedical subjects

M W Craig

Publications and source records attributed to M W Craig.

14 recordsLinked to original sources
PubMed1983

"Living up to par"--a golf tournament for persons with COPD.

An attempt to provide an improved quality of life for COPD patients led to the development of a prototype training program. The final outcome of an initial five-month program was a COPD golf tournament. The program included didactic education sessions, practice golf sessions to increase physical endurance, and the final competitive tournament. The expectations for this program were (1) that because these patients' self-confidence would improve through training, they could serve as role models for other COPD individuals in the community; and (2) that by learning breathing retraining techniques and coupling them with exercise, these patients would raise their tolerance levels, which could benefit other forms of activity in addition to golfing. We found that 7 of the 8 patients involved did increase their self-confidence, as evidenced by their being able to compete in a tournament that was covered by the news media. They also served as role models, as shown by an increase in physicians referrals to the overall program and by other persons with COPD calling the hospital to inquire about rehabilitation training. The second expectation proved to be correct as 7 of the 8 patients began by being able to comfortably play 4 to 6 holes in 2 hours, and 7 of the 8 showed improvement by being able to play 6 to 9 holes in the same time span. There appeared to be subjective improvement as well when the patients applied techniques learned to daily routine activities. We conclude that our innovative method of pulmonary rehabilitation was successful in achieving standard rehabilitation goals, was not costly, and was a safe, enjoyable means of outpatient rehabilitation.

Golf↗
PubMed1982

Once-daily pindolol in hypertension: an ambulatory assessment.

Ambulatory monitoring of intra-arterial blood pressure was used to assess patterns of circadian blood pressure in 12 hypertensive patients who were treated with pindolol in either a once- or twice-daily dosage regimen. Neither once-daily nor twice-daily pindolol had much effect during the latter part of the night and early morning. In the six patients who agreed to further crossover studies, the hypotensive effects of once-daily therapy were not significantly different from those produced by a twice-daily regimen. While confirming the effectiveness of once-daily beta blockade in hypertension, we deduce that failure to affect nighttime blood pressure substantially is a feature independent of the dosage regimen and also, probably, of the individual beta blocker used.

Adult↗
PubMed1982

Coital blood pressure in hypertensives. Cephalgia, syncope, and the effects of beta-blockade.

During the continuous monitoring of intra-arterial blood pressure in ambulant hypertensive subjects, 18 episodes of coitus were recorded in 11 subjects. Peak values of up to 300/175 mmHg found, the mean for men being 237/138 mmHg and for women 216/127 mmHg. Two patients with coital symptoms (cephalgia and syncope) showed no unusual responses and, when restudied after beta-blockade, one subject showed no reduction in peak coital blood pressure. The results complement those found previously in normal subjects and demonstrate the potential of the technique in investigating coital symptoms.

Adrenergic beta-Antagonists↗
PubMed1981

Once daily beta-adrenoceptor blockade in hypertension: an ambulatory assessment.

1 The ambulant intra-arterial blood pressure of eighteen hypertensive subjects was monitored before and again after 3 months treatment with thrice daily sotalol (six patients), twice daily pindolol (six patients) and once daily pindolol (six patients). 2 Three patients in the sotalol group underwent a third study having changed to a once daily regimen; similarly six patients in the pindolol groups were restudied having crossed over to the alternative pindolol dosing regimen, total daily dosage being maintained in all cases. 3 Comparison of 24 h blood pressure curves before and after treatment showed effective daytime reduction but less consistent effects at night. 4 In the crossover experiments once daily and multiple daily dosing regimens produced identical patterns of reduction over 24 h in both blood pressure and heart rate. 5 It is inferred that in the treatment of hypertension, once daily dosing with standard preparations of beta-adrenoceptor blocking agents is probable adequate.

Adrenergic beta-Antagonists↗
PubMed1980

Ambulant blood pressure: reproducibility and the assessment of interventions.

1. We have assessed the day-to-day reproducibility of intra-arterial blood pressure by monitoring 17 freely ambulant hypertensive patients for a period of 48 h. Eight had no change of therapeutic regimen throughout and nine took a single dose of a hypotensive agent before retiring on the second night. 2. Records were analysed to provide hourly mean values of heart rate, systolic and diastolic blood pressure. No significant differences between first and second day recordings were found except after the intervention in the second group. 3. Allowing subjects to follow their normal daily routine produces inevitable variation in their pattern of physical and other activity. However, by the use of these methods of recording and analysis, with pooled measurements from a small group of subjects, reproducibility is sufficiently good to permit the reliable assessment of therapeutic interventions.

Activities of Daily Living↗
PubMed1980

Propranolol LA and ambulatory blood pressure.

1 The technique of continuous recording of intra-arterial blood pressure in ambulant hypertensives has been used to investigate the effects of a long-acting formulation of propranolol (propranolol LA). 2 Seven subjects with untreated essential hypertension were studied before and 2 months after commencing treatment with propranolol LA once daily in the morning, results showing that smooth control of blood pressure and heart rate occurred throughout 24 h. 3 Bicycle ergometry tests performed by these subjects during both studies showed significant blood pressure reduction by propranolol LA during the mild and moderate grades of dynamic exercise. 4 In a parallel study where six treated hypertensives were monitored before and after substitution of standard propranolol by the 'LA' form, close correspondence of blood pressure throughout the 24 h occurred with each regimen.

Adult↗
PubMed1979

Physical activity and the circadian rhythm of blood pressure.

1. Ambulatory blood pressure monitoring was carried out in 10 subjects for a period of 48 h, the first or second 24 h part of which was selected randomly to be a period of complete bed rest. 2. Heart rate was significantly lower throughout the period of bed rest except for the period 04.00-08.00 hours, when there was little difference. 3. The circadian variation of blood pressure was reduced during the day of bed rest but this was mainly due to higher night-time pressures.

Adult↗
PubMed1979

The effects of metoprolol on ambulatory blood pressure.

1. Continuous monitoring of arterial pressure was performed via an indwelling cannula over 24 h in 12 hypertensive patients before treatment and again 2-4 months after starting metoprolol (100 mg twice daily). 2. During treatment, heart rate and systolic and diastolic pressures were significantly reduced. 3. The circadian patterns of heart rate and blood pressure changes were similar before and during therapy.

Adult↗