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Biomedical subjects

M W Gregory

Publications and source records attributed to M W Gregory.

At least 37 records · Page 2Linked to original sources
PubMed1986

Tissue-invading ciliates associated with chronic colitis in a horse.

Ciliates resembling Polymorphella ampulla (Dogiel, 1929) were found in large numbers in the crypts and lamina propria of the caecum and colon of a one-year-old Thoroughbred gelding that had shown recurring bouts of chronic diarrhoea and weight loss over a 5-month period. A heavy burden of helminths, mainly cyathostomes (trichonemes) was present at post-mortem examination and no significant bacterial pathogens were recovered. It was considered that the Polymorphella (which is normally a commensal organism) had in this case assumed a secondary pathogenic role.

Animals↗
PubMed1985

Pathogenicity of the coccidium Eimeria crandallis in laboratory lambs.

Ten colostrum-deprived, coccidia-free lambs were reared artificially in indoor cages. At 4 weeks of age they were allocated to 5 groups of 2: Groups 1-3 received 10(4), 10(5) and 10(6) sporulated oocysts of Eimeria crandallis/lamb respectively, each as a single inoculum. Group 4 lambs received daily doses increasing over a 4-week period. Groups 1-3 showed diarrhoea and weight loss from about day 14, followed by slow recovery from about day 30. The diarrhoea was accompanied by a wave of oocyst output and a reduction in serum albumin and plasma alkaline phosphatase activity. One lamb in group 4 died of an unrelated condition on day 15; the other showed no clinical effect of the oocyst inoculations and its oocyst output was related only to the first week or two of inoculation. Lambs in Group 1 showed no clinical effect or oocyst output following challenge with 10(6) oocysts on day 28. E. crandallis showed high pathogenicity and immunogenicity. Its pathogenicity was not closely related to infecting dose within the range 10(4)-10(6).

Alkaline Phosphatase↗
PubMed1983

Observations on the epidemiology of coccidial infections in sheep under varying conditions of intensive husbandry including chemoprophylaxis with monensin.

Coccidiosis occurs sporadically in lambs at about 6 weeks of age when oocyst output is very high in healthy as well as in diseased lambs. These experiments were designed to throw light on the source of infection and to correlate oocyst output in lambs and ewes with performance in lambs. In two experiments, one indoors on deep litter the other in outdoor paddocks, oocyst output (of different coccidial species), body weight and clinical state of lambs were recorded weekly. Oocyst output in ewes was also recorded, starting 1-4 weeks before lambing. Monensin was included in the concentrates of ewes and/or lambs, up to lambing or before and after lambing. No periparturient rise was detected in the oocyst output of ewes. Monensin drastically reduced oocyst output in animals receiving it. Oocyst output in lambs appeared to be little affected by the output of ewes around the lambing period, but was reduced if the ewes' output was kept low after lambing. Lambs receiving monensin tended to produce drier faeces but their weight gain was not significantly greater than that of controls. Eimeria crandallis was the predominant species in the lambs, followed by E. ovinoidalis and E. ovina.

Animal Husbandry↗
PubMed1982

Medication against ovine coccidiosis--a review.

Data published since 1940 on the use of drugs to prevent or treat ovine coccidiosis are presented in the form of tables. These highlight the differences in conditions of husbandry and mode of administration. Such differences partly account for the variability of response to medication. Drugs that have proved useful under certain conditions include amprolium, monensin and lasalocid for prevention, and sulphonamides for treatment.

Animals↗
PubMed1981

Mites of the hedgehog Erinaceus albiventris Wagner in Kenya: observations on the prevalence and pathogenicity of Notoedres oudemansi Fain, Caparinia erinacei Fain and Rodentopus sciuri Fain.

The occurrence of 3 mites (Acari: Astigmata) is reported, from the Central African hedgehog Erinaceus albiventris Wagner, the the Nairobi area of Kenya. Notoedres oudemansi Fain (Sarcoptidae) showed sporadic incidence, infected males particularly and caused high mortality. A description of the male mite is given. Caparinia erinacei Fain (Psoroptidae) was found on 72% of animals on capture but showed very low pathogenicity. Rodentopus sciuri Fain (Hypoderidae) was found in the hair follicles of 46% of 43 animals examined; adverse effects were slight.

Animals↗
PubMed1981

Globule leucocytes and Peyer's patches in lambs infected with coccidia.

In a study of intestinal tissues from worm-free lambs experimentally infected with coccidia, the population of globule leucocytes was on average nine times higher in the mucosa overlying Peyer's patches than in the adjacent mucosa. Mucosal mast cell populations in the two areas were not significantly different. There was evidence of increased migration of globule leucocytes into the villus epithelium in response to coccidial infection.

Animals↗
PubMed1975

Arthroderma benhamiae infection in the Central African hedgehog Erinaceus albiventris, and a report of a human case.

The occurrence of ringworm caused by Arthroderma benhamiae Ajello & Cheng is reported in Central African hedgehogs (Erinaceus albiventris Wagner), caught near Nairobi, Kenya. Of the 45 animals examined, 10 were positive on culture, including a litter of 4 young. Six infected animals were without lesions, and 2 littermates showed scaly areas similar to those described in E. europaeus L. caused by Trichophyton erinacei (Smith & Marples) Padhye & Carmichael. No correlation with mite infestation or mange lesions was evident. Ringworm-like lesions were found which were repeatedly negative on culture. A human infection by A. benhamiae was contracted from the hedgehogs.

Age Factors↗