Biomedical subjects

M W Scriven

Publications and source records attributed to M W Scriven.

28 records · Page 2Linked to original sources

PubMed1993

Hepatic 'pseudotumours': an important diagnostic pitfall.

Hepatic 'pseudotumours' are radiological abnormalities which give the appearance of tumour. They may be focal areas of disease such as fatty infiltration or areas of focal sparing in diffuse processes. We present four cases of hepatic 'pseudotumours' due to diffuse fatty infiltration with focal sparing and emphasise the need for further radiological assessment of focal lesions found on ultrasound scanning. Measurement of CT attenuation allows a confident diagnosis of fatty infiltration with focal sparing, thus preventing unnecessary investigation. Other forms of hepatic pseudotumour may require further investigation.

Adult↗

PubMed1993

Cholecystectomy: a study of patient satisfaction.

A prospective study of 77 patients undergoing open cholecystectomy was undertaken to establish the degree of satisfaction experienced by these patients. Specific symptoms were recorded preoperatively and at one year postoperatively. Two patients died from unrelated diseases during the year of follow-up and were excluded from the analysis. All symptoms inquired about reduced in frequency postoperatively, the best cures being achieved for jaundice, upper abdominal colic, fatty food intolerance and back/shoulder pain. A third of patients developed at least one new symptom during the year of follow-up. Seventy-seven per cent graded themselves either completely or well satisfied. It was not possible to predict from preoperative symptoms those who would be dissatisfied or those who would develop a new symptom. This study refutes recent suggestions that up to 50% of patients are dissatisfied with cholecystectomy and provides data which may be used to counsel patients preoperatively.

Cholecystectomy↗

PubMed1992

Elevated serum CA 19-9 levels in hepatobiliary cystadenoma with mesenchymal stroma. Two case reports with immunohistochemical confirmation.

Hepatobiliary cystadenomas with mesenchymal stroma (CMS) are rare tumors. Two cases are reported that illustrate many features of CMS, including polypoid involvement of the common hepatic duct in one case. Both tumors were associated with elevated serum levels of the tumor-associated antigen CA 19-9 but normal levels of carcinoembryonic antigen and alpha-fetoprotein. Immunohistochemical analysis confirmed the presence of CA 19-9 in the epithelial component of the tumor. The implications of these findings are discussed, both in relation to the histogenesis of CMS and its preoperative diagnosis. A minimally elevated level of CA 19-9 was found in only one of five patients with hydatid disease of the liver, an important differential diagnosis in clinical management.

Adult↗

PubMed1992