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Biomedical subjects

M W Wolcott

Publications and source records attributed to M W Wolcott.

14 recordsLinked to original sources

Postpneumonectomy tension chylothorax.

Chylous leak from the thoracic duct into the pleural space may occur after any type of thoracic surgery. This is a serious, often life-threatening entity. Two cases of postpneumonectomy chylothorax with hemodynamic compromise are reported. Early recognition, pathophysiology, and optimal management of this problem are discussed.

Aged↗

Changes in the interstitial fluid and the muscle water in rabbits in hemorrhagic shock.

Dynamics and changes in the biochemical composition in the interstitial fluid and the muscle water were studied in hemorrhagic shock. The interstitial fluid was collected from implanted perforated capsules. Muscle biopsies were examined with regard to their water content by the steady state magnetic nuclear resonance spectroscopy. The consistent and what appears to be the most significant changes were the fall in the interstitial fluid pressures, the quantitative reduction of muscle water, a sharp fall in the blood and interstitial blood pH, the moderate hyperkalemia and lack of change in blood an interstitial fluid sodium, and the rise in blood glucose levels not accompanied by a rise in the interstitial fluid glucose levels.

Animals↗

Discontinuance of immunosuprression in renal transplant patients.

Immunosuppressive therapy was discontinued in six patients for an average of 27 months. In these six patients, only two rejections have occurred. A survey of other transplant centers showed that in such patients rejection was often delayed weeks or months after therapy was stopped. Once immunosuppressive therapy has been stopped, for whatever reason, and rejection has not occurred, consideration should be given to not resuming therapy unless signs of rejection appear.

Graft Rejection↗