PubMed HealthSearch

Biomedical subjects

M Waisman

Publications and source records attributed to M Waisman.

17 recordsLinked to original sources

[Conservative treatment of CSF leakage after lumbosacral operations].

CSF leakage through a postoperative lumbosacral wound is an uncommon complication. It may result from excessive traction on nerve roots, or direct trauma or laceration at operation, causing inadvertent opening of the dura (1,4). Other reasons for this complication are residual bone spikes postlaminectomy, traumatic myelography puncture (2), and improper suture of dural defects. We examined 8 patients who had postoperative CSF leakage as the sole complication of lumbosacral spinal operations. They were all treated conservatively with bed rest in the Trendelenburg position, antibiotic coverage, watertight skin suturing and daily subcutaneous puncture. Each patient had been operated on for a different condition.

Cerebrospinal Fluid

Postoperative cerebrospinal fluid leakage after lumbar spine operations. Conservative treatment.

Cerebrospinal fluid (CSF) leakage from a postoperative wound after lumbar spine operation is an uncommon complication. It may result from excessive traction of the nerve roots, direct trauma, or laceration at the time of operation, causing the dura to be inadvertently opened. Other reasons for this complication are postlaminectomy residual bone spikes, traumatic myelography puncture, and improper suture of dura defects. Eight patients who had postoperative CSF leakage as the only complication after lumbosacral spine operations were examined. They were all treated conservatively with bed rest in the Trendelenburg position, antibiotic coverage, watertight skin suturing, and daily subcutaneous punctures. No patient was operated on for the same type of complication.

Adult

[Posterior approach for excision of sacral chordoma].

Chordoma is considered to be a malignant, fatal tumor. According to most authors it constitutes between 1-4% of all malignant bone tumors. In 50% of the cases it is located in the sacrum, in 35% in the cervical spine and skull, and in 15% in the thoracic spine and elsewhere. It is an aggressive, locally invasive, slowly-growing tumor. Although metastases are rare, when they occur they are of an anaplastic type, especially in the lungs, liver, regional lymph nodes, skin and muscles. Chordoma is a rare tumor, and its location and slow growth often result in delayed diagnosis. Complete excision of the chordoma was formerly considered impossible. There is often local recurrence, and often, by its very nature, excision results in neurological defects. Lately, there is more optimism regarding complete cure, due to more advanced surgical methods. We present a 66-year-old man in whom a tumor developed in the sacrococcygeal area and the right buttock. The tumor was diagnosed by CT, MRI and biopsy as a chordoma of the sacrum, without intra-abdominal infiltration. He was operated through a posterior approach, with complete resection of the tumor, including almost the whole sacrum and the coccyx. We consider this approach simpler than the abdominal-dorsal approach, which in cases of intra-abdominal infiltration is necessary. We regard this simple incision as a significant advance in the treatment of this condition.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged

A clinical look at the aging skin.

The aging Caucasian skin becomes yellow, dry, wrinkled and inelastic. Deterioration increases its susceptibility to malignant neoplasms, pruritus, and candidal infection. In addition, psychosomatic problems vascular disease, "little strokes," and chronic malnutrition may precipitate or exacerbate skin disorders in the elderly. Treatment with "strong" medications should be taboo because of the fragility of senile skin. The risk of toxic reactions or of allergic sensitization is great. Because healing is retarded in old tissue, time is an indispensable component of successful treatment.

Adolescent

Tumor of the follicular infundibulum.

A histopathologically unique tumor originating from the infundibular portion of vellus hair follicles is presented and the clinical and microscopic features of such a case are described. A superficial subepidermal shelf of trichilemmal structure differentiates the lesion from the lobular acanthosis of trichilemmoma.

Hair Diseases

Basal cell nevus syndrome in a black patient: report of a case and review of the literature.

An 80-year-old black man had multiple basal cell epitheliomas (BCEs), palmar pits, and mandibular cysts. This patient is unusual, not only because of multiple BCEs, but also becuase they developed when the patient was at age 77. Only three other black patients with multiple BCEs in association with basal cell nevus syndrome have been reported previously.

Black or African American

Carcinoma of the inframammary crease.

Carcinoma of the inframammary crease is an uncommon but distinctive manifestation of carcinoma of the breast. This report of a case illustrates the clinical and histophathologic features. The patient's tumor was exophytic and fissured, and the initial biopsy specimen mimicked basal cell epithelioma.

Adenocarcinoma

Topical clindamycin in acne vulgaris. Safety and stability.

Eighteen patients with acne vulgaris used a hydroalcoholic solution of clindamycin hydrochloride topically. Serum samples were obtained and assayed for clindamycin; no evidence for systemic absorption was found. The clindamycin capsules used in this preparation contained insoluble fillers that may be removed by filtration without loss of in vitro antibacterial activity. This solution is stable for at least six months.

Acne Vulgaris

Lichen aureus.

A case of lichen aureus is described to record its clinical and histopathologic features. The disease is a variant of the pigmented purpuric eruptions, the common characteristic of which apparently resides in an abnormality of the minute cutaneous blood vessels.

Adult

Bullous transient acantholytic dermatosis.

We have been three cases of a bullous variant of transient acantholytic dermatosis. Skin biopsy specimens showed histopathologic changes identical to pemphigus foliaceus, but immunofluorescent studies showed no tissue-fixed or circulating antibodies to intercellular antigens. The bullous eruption lasted a few weeks to several months and healed without scarring or recurrence. The lesions healed with topical and/or systemic corticosteroid therapy.

Acantholysis

Maculopapular eruption in hypoparathyroidism.

A 12-year-old girl with idiopathic hypoparathyroidism manifested an erythematous, follicular, maculopapular eruption on her truck and arms. The eruption abated when the serum calcium rose to normal levels.

Child

Experimental study on healing of bone fractures using L-dopa.

Internal fixation with plate and screws was combined with administration of L-Dopa, which presumably operates by stimulating release of growth hormone. The combination induces osteogenesis, callus formation and complete union in the experimental femur osteotomy gap (10-20 mm long). Complete clinical and radiologic union was achieved in dogs treated for 3-6 weeks, thus achieving healing of a bone gap which otherwise would have formed a pseudarthrosis.

Animals