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Biomedical subjects

M Wietlisbach

Publications and source records attributed to M Wietlisbach.

10 recordsLinked to original sources

[Insulin as an anabolic: hypoglycemia in the bodybuilding world].

Excessive body building may be dangerous. To promote athletic performance and to improve physical appearance many of the body builders abuse anabolic-androgenic steroids and other drugs. The abuse of insulin as an anabolic medication in this athletic community was followed by a case of severe hypoglycaemia in a body builder. A 30-year old male presented with cerebral symptoms of hypoglycaemia. Directly before an international competition he tried to stimulate muscle growth by using the hypoglycaemic stimulus to the growth hormone. To achieve this he injected 70 IE of a short-acting insulin subcutaneously, resulting in severe hypoglycaemia. After the initial administration of intravenous glucose by the paramedics, he lost consciousness and showed signs of convulsions. After orotracheal intubation by an emergency physician, despite of ongoing infusion of glucose the blood glucose concentration remained low as measured in the out-of-hospital setting. Finally administration of additional glucose and glucagon in the intensive care unit was able to stabilize the metabolic system. In any case of severe hypoglycaemia, repetitive measurements of blood glucose even in the prehospital setting should be performed to detect the hypoglycaemia especially if athletes are concerned.

Adult

Learning manual skills in anesthesiology: Is there a recommended number of cases for anesthetic procedures?

UNLABELLED: The learning process is a multidimensional function with a wide intra- and interindividual scattering. To determine the learning process in anesthesia, we evaluated 11 first-year residents according to their rate of success or failure when applying manual anesthesiological skills, such as performance of spinal, epidural, or brachial plexus anesthesia and tracheal intubation or insertion of an arterial line. Epidural anesthesia was the most difficult procedure (P < 0.05). Significant differences were found between epidural anesthesia and tracheal intubation (P < 0.05), insertion of an arterial line (P < 0.05), and brachial plexus block (P < 0.05), as well as between spinal anesthesia and orotracheal intubation (P < 0.05). Learning curves are a valid tool for monitoring institutional and individual success. IMPLICATIONS: To investigate the learning process in anesthesia, typical anesthetic procedures were performed by inexperienced residents during their first year. Learning curves were generated for each procedure performed. Epidural anesthesia was the most difficult procedure to perform (P < 0.05).

Anesthesia, Epidural

[Oxygen embolism after use of hydrogen peroxide in thoracic surgery].

UNLABELLED: Hydrogen peroxide is often used for irrigation of surgical wounds. In the presented two cases hydrogen peroxide was used to irrigate the thoracic cavity after thoracotomy for lung surgery. After irrigation with hydrogen peroxide only one patient showed clinical signs of pulmonary embolism. In both cases the postoperative recovery was uneventful. In one of the cases transesophageal echocardiography showed air bubbles, a sign of oxygen embolism, passing the right heart. CONCLUSION: The application of hydrogen peroxide in preformed cavities, such as the thoracic, should be avoided.

Echocardiography

[Resuscitation].

By the measures of basic life support (BLS) as well as those of advanced cardiac life support (ACLS) a large portion of the 8,000 to 10,000 victims of sudden circulatory arrest in Switzerland might be resuscitated successfully without permanent neurological deficits. Prerequisites are an early installation of measures as well as the control of the rationale and the individual techniques by trained personnel. The single most important measure is electric defibrillation of ventricular fibrillation. With the aid of automatic defibrillators it can be made available to a wider range of users. Pharmacotherapy is of minor importance.

Algorithms

[Venous access and methods of drug application in ACLS (Advanced Cardiac Life Support)].

After initiation of cardiopulmonary resuscitation [CPR] with ventilation, chest compression and defibrillation when necessary, venous access, which allows administration of drugs and fluids, is the next measure. A large diameter peripheral vein should be the first choice and should be cannulated with a plastic catheter. If this is delayed or impossible, alternative routes such as central iv lines, intraosseous infusion or endobronchial drug administration should be considered.

Catheterization, Peripheral

[Pharmacotherapy in resuscitation].

Although pharmacologic intervention has traditionally been a mainstay in the treatment of circulatory collapse and cardiac arrest, a critical reappraisal of the relevant literature does not support this stance in every case. During cardiac arrest, medications take second place to other forms of intervention: initiation of basic life support with ventilation [100% oxygen!], chest compression and defibrillation if indicated. Epinephrine is still the drug of choice in all types of cardiac arrest. Atropine is recommended for asystole and pulseless electrical activity [PEA] with bradycardia, while lidocaine has a place in the therapy of persistent ventricular fibrillation. Sodium bicarbonate is of only limited benefit in special cases.

Adrenergic Agonists

[Results of 35 ambulatory gamete transfers: evaluation of a successful method using regional anesthesia].

Thirty-five ambulatory gamete transfers were performed in 29 patients, resulting in a pregnancy rate of 40% and a take-home baby rate of 26%. Upon request 10 transfers in 9 patients were done under epidural anesthesia. The avoidance of general anesthesia allows the patient to consciously participate in her treatment and improves postoperative recovery. Our results suggest that gamete transfer procedures can be carried out under epidural anesthesia with no adverse effects on the pregnancy rate.

Anesthesia, Epidural