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M X Zarrow

Publications and source records attributed to M X Zarrow.

81 records · Page 5Linked to original sources
PubMed1965

Rabbit: frequency of suckling in the pup.

Rabbit does were given free access to their young, access once a day, and access twice a day. In all three groups the young were nursed only once every 24 hours. Growth curves for the pups from day 2 of age to day 30 were identical for all three groups. The restriction of suckling to once a day appears to depend on the mother and not the pups.

Animals↗
PubMedDate not supplied

Influence of olfactory bulbectomy and the serotonergic system upon intermale aggression and maternal behavior in the mouse.

Biochemical parameters in the brains of olfactory bulbectomized male and female mice were studied in two experiments, followed by three experiments in which 5-HTP was injected into bulbectomized males and females to try to block abnormal behaviors. In Experiment 1 bulbectomized male and female mice had significantly less tryptophan hydroxylase in their brains than did sham controls. Neither 5-hydroxtryptophan decarboxylase nor tyrosine hydroxylase activity was affected. In Experiment 2 the rate of synthesis of 5-HT was significantly less in bulbectomized males and females. Since bulbectomy leads to increased pup killing by female mice, the objective of Experiments 3 and 4 was to see whether the injection of 5-HTP into bulbectomized females could block this behavior. The incidence of pup killing was not influenced, but in both studies the latency to kill was significantly prolonged. Olfactory bulbectomy eliminates aggressive behavior in male mice, and the purpose of Experiment 5 was to determine whether 5-HTP treatment could restore normal levels of aggression. No significant effect was found. The data suggest that a dual mechanism is needed to explain the behavioral abnomalities seen in the two sexes; the mechanism in the female appears to be serotonergic while that in the male is still unknown.

5-Hydroxytryptophan↗