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Biomedical subjects

M Y Song

Publications and source records attributed to M Y Song.

11 recordsLinked to original sources

Foreign-body granuloma occurring in the mandible subsequent to orthognathic surgery: a case report.

We report the first case of foreign-body granuloma occurring in the mandible of a patient with a history of orthognathic surgery. A 20-year-old male patient had a hard swelling and pain in the left mandibular angle and the parotid area. Plain radiographs showed a radiolucent lesion extending from the buccal area under the left sigmoid notch of the mandible to the mandibular angle. Computed tomographs showed an expanded osteolytic mass in the same area, with destruction of most of the bone on the buccal side. A microscopic examination revealed filamentous foreign material associated with chronic inflammatory cell infiltration and an aggregation of multinucleated giant cells. Foreign-body granuloma in the mandible, although rare, should be included in the differential diagnosis in cases of postoperative masses.

Adult↗

A comparative study of the radiological diagnosis of postoperative maxillary cyst.

OBJECTIVES: To compare the diagnostic accuracy for the postoperative maxillary cyst (POMC) of panoramic in combination with Waters' radiography with computed tomography (CT) and of oral and maxillofacial radiologists with non-specialists. STUDY DESIGN: Nineteen cases of POMC and 19 of postoperative changes were assessed using panoramic in combination with Waters' radiographs and CT by five oral and maxillofacial radiologists and five non-specialists on a five-point scale. The areas under the ROC curves were analysed using the Wilcoxon rank sum test to determine any differences in diagnostic accuracy between the two methods and between the two groups. RESULTS: The diagnostic accuracy of CT was higher than that of combined panoramic and Waters' radiographs for the oral and maxillofacial radiologists (P < 0.05), but not for the non-specialists (P > 0.05). The diagnostic accuracy of the oral and maxillofacial radiologists for each method was higher than that of the non-specialists group (P < 0.05). CONCLUSIONS: CT improves the evaluation of POMC. Radiological training and experience leads to more accurate diagnoses.

Adult↗

Diagnostic imaging of pigmented villonodular synovitis of the temporomandibular joint associated with condylar expansion.

Pigmented villonodular synovitis (PVNS) is a rare lesion of the temporomandibular joint. We report a case which was initially misdiagnosed as a parotid tumor. CT revealed a well-defined mass demonstrating higher attenuation than the adjacent soft tissue with marked expansion of the mandibular condyle. MRI clearly delineated the extent of the lesion which had very low signal intensity on both T1W and T2W sequences due to the effect of hemosiderin. The usefulness of these imaging procedures in diagnosis of PVNS is discussed.

Diagnosis, Differential↗

Osmotic effects as a factor modifying insecticide toxicity on Aedes and Artemia.

Euryhaline species are more tolerant of various insecticides under isosmotic conditions. Two euryhaline species, Aedes taeniorhynchus (Wiedemann) and Artemia sp., were exposed to four insecticides (aldicarb, dimethoate, imidacloprid, tebufenozide), under isosmotic and hyperosmotic conditions. Mortality under these two osmotic conditions was observed and compared to evaluate salinity as a contributing factor to insecticide toxicity. Artemia was more tolerant of all chemicals tested than A. taeniorhynchus under isosmotic conditions based on the percentage mortality observed. Mortality of Artemia under isosmotic conditions was dependent on the length of exposure; A. taeniorhynchus did not exhibit time dependence. Less mortality was observed in populations of both test species under isosmotic conditions compared with hyperosmotic conditions. However, the variation in mortality due to exposure to test chemicals was of greater magnitude in A. taeniorhynchus than Artemia. This result indicates that higher salinity is a greater stress on A. taeniorhynchus than Artemia when exposed to the test insecticides at the concentration ranges tested in this study.

Aedes↗

Analysis of interphase cells for the Philadelphia translocation using painting probe made by inter-Alu-polymerase chain reaction from a radiation hybrid.

Fluorescence in situ hybridization (FISH) probe for the identification of the Philadelphia (Ph) translocation [t(9;22) (q34;q11)] in chronic myelogenous leukemia cells was developed by inter-Alu-polymerase chain reaction of DNA from an interspecific somatic cell hybrid containing approximately 5 Mb of human DNA covering the ABL gene region on human chromosome 9q34. This probe was large enough to be effective in identifying the genomic domains yet small enough to resolve them in more than 90% of bone marrow interphase cells. Combination of the probe with a cosmid contig probe for the BCR region of chromosome 22 in two-color FISH reduced the frequency of false-positive identification of the Ph chromosome to less than 1%. The procedure allows detection of as few as 1% Ph+ cells independent of the cycling status or BCR/ABL expression level of cells, and the quantitation of non-Ph chromosome-containing interphase nuclei in the marrow of patients judged 100% Ph+ by standard cytogenetics.

Humans↗

Coexistence of diabetes and hypertension results in unique structural alterations in the renal artery in rats beyond that found with diabetes alone.

Numerous investigators have presented evidence of increased mortality in patients with diabetes mellitus due to cardiovascular disease. It is still unclear as to the reasons why there is a predisposition to vascular pathology that in the advanced state leads to atherosclerosis. Our hypotheses were: (1) The condition of diabetes mellitus in a streptozocin animal model may show vascular changes similar to early pathology in macrovessels and (2) since the model is normotensive, inducing hypertension will result in early atherogenic pathology. We carried out a quantitative analysis of the renal artery using light and electron microscopy to test the hypotheses. Male Wistar rats had diabetes mellitus induced using streptozocin and 1 week later half of the diabetic animals had hypertension induced with deoxycorticosterone acetate (DOCA). Samples were taken following 7 weeks of diabetes, or 7 weeks of diabetes with DOCA administration during the final 6 weeks. The renal artery from the diabetic group did not have any differences in wall or luminal dimensions from control, but did have proportionately more extracellular matrix than smooth muscle in the tunica media. This is evidence of structural change, in a large supply artery, as a manifestation of diabetes mellitus, similar to that seen in vascular disease. Vessels from the control/hypertensive had a significantly thickened tunica media as did the diabetic/hypertensive over control values. The latter also had proportionately even greater significant elevation of the extracellular matrix compared with either the diabetic or control/hypertensive. In addition, only the diabetic/hypertensive group showed marked subendothelial invasion of macrophage type cells and deposits of various shapes and densities. We have, therefore, demonstrated significant vascular alteration due to the diabetic condition in this animal models and also shown that with hypertension and diabetes combined, the early vascular pathology is exacerbated.

Animals↗

Ureteral metastases--computed tomographic findings.

CT findings in three cases of ureteral metastases are reported. Metastases to the ureter is an uncommon cause of the upper urinary tract obstruction. The most common primary sites include breast, stomach and neoplasms from pelvic organs. Radiographic studies revealed an ureteral stenosis in all the presenting cases. CT scans demonstrated a thickened regular ureteral wall at the level of the narrowing and no other abnormalities of the retroperitoneum. Such CT features suggest the possibility of ureteral metastases in a patient with the appropriate clinical setting. Histological studies, whenever possible, must confirm these radiographic findings. Early recognition of ureteral metastases and appropriate treatment for relief of urinary tract obstruction may prolong survival time.

Adenocarcinoma↗

Recurrent pheochromocytoma: intrarenal and pulmonary spread.

A case of intrarenal malignant pheochromocytoma, closely resembling hypernephroma radiologically, is presented. This tumor with 2 other pulmonary masses, recurred 12 years after ablation of an adrenal pheochromocytoma and extended into the inferior vena cava.

Adrenal Gland Neoplasms↗

Radiologic features of a metastatic carcinoma to the ureter.

2 cases of metastasis to the ureter from carcinoma of the stomach are presented. The clinical and radiologic features are reviewed. Metastasis to the ureter is rare. A plea for vigorous evaluation and early detection of this entity is made.

Adenocarcinoma↗