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Biomedical subjects

M Y Wee

Publications and source records attributed to M Y Wee.

8 recordsLinked to original sources
PubMed1993

Isoflurane in labour.

A comparison of the analgesic efficacy of Entonox (50% nitrous oxide in oxygen) and Entonox with 0.2% isoflurane was made in 18 consenting mothers during the first stage of labour. The inhalational gases were self-administered during contractions over a 3 h study period using a standard Entonox demand valve and breathing system. Isoflurane 0.2% was added from an Ohmeda Isotec drawover vaporizer and the inspired concentration of isoflurane was analysed continuously using a Datex Ultima analyser. Linear analogue scores for pain were significantly lower (p < 0.001) during the Entonox-isoflurane administration compared with Entonox alone. Drowsiness was not a clinical problem and there was a high acceptance rate for Entonox-isoflurane inhalational analgesia during labour.

Adolescent↗
PubMed1992

A method to facilitate regional anaesthesia by detection of mixed nerve action potentials.

We have studied conduction anaesthesia of the median and ulnar nerves at the axilla using mixed nerve action potentials (MNAP) as a guide to needle position in three volunteers. The median and ulnar nerves were stimulated distally at the wrist using surface electrodes and MNAP were detected proximally in the axilla using an insulated needle electrode. The increase in amplitude of MNAP to maximum as the insulated needle electrode approached the nerve trunk was taken as an indication that the tip of the needle was in close proximity to the nerve trunk. Instillation of 1% lignocaine plain 4 ml decreased the amplitude of the MNAP with the onset of nerve block. We conclude that this method may be of potential use as an aid to peripheral regional anaesthesia by allowing accurate localization of needle position close to specific nerve trunks.

Anesthesia, Conduction↗
PubMed1992

Spinal anaesthesia for caesarean section: comparison of 22-gauge and 25-gauge Whitacre needles with 26-gauge Quincke needles.

We have studied 150 women undergoing elective Caesarean section under spinal anaesthesia. They were allocated randomly to have a 22-gauge Whitacre, a 25-gauge Whitacre or a 26-gauge Quincke needle inserted into the lumbar subarachnoid space. The groups were compared for ease of insertion, number of attempted needle insertions before identification of cerebrospinal fluid, quality of subsequent analgesia and incidence of postoperative complications. There were differences between groups, but they did not reach statistical significance. Postdural puncture headache (PDPH) was experienced by one mother in the 22-gauge Whitacre group, none in the 25-gauge Whitacre group and five in the 26-gauge Quincke group. Five of the six PDPH occurred after a single successful needle insertion. Seven of the 15 mothers in whom more than two needle insertions were made experienced backache, compared with 12 of the 129 receiving two or less (P < 0.001). We conclude that the use of 22- and 25-gauge Whitacre needles in elective Caesarean section patients is associated with a low incidence of PDPH and that postoperative backache is more likely when more than two attempts are made to insert a spinal needle.

Adolescent↗
PubMed1991

The oesophageal detector device. An assessment with uncuffed tubes in children.

In 100 children between the ages of 1-10 years, observers of differing experience reliably and rapidly detected 50 oesophageal and 50 tracheal intubations in a randomised single-blind trial using the original oesophageal detector device. However, only two children under the age of 2 years were tested and no conclusions can be drawn for this age group from this study.

Child↗
PubMed1988

The oesophageal detector device. Assessment of a new method to distinguish oesophageal from tracheal intubation.

A new method to distinguish oesophageal from tracheal intubation using the oesophageal detector device was evaluated. In 100 healthy adults, observers of differing experience reliably and rapidly detected 51 oesophageal and 49 tracheal intubations in a randomised, single-blind trial. In one case, blockage of the tracheal tube was detected swiftly and allowed corrective steps to be taken. This method can be used in patients with bronchospasm to detect correct tracheal placement when auscultation and decreased compliance of the chest may make clinical confirmation difficult. It can be concluded from this study that the oesophageal detector device is a reliable, rapid, inexpensive and easy to use method for the detection of oesophageal intubation and its very low cost should make it readily available in all situations where tracheal intubation is carried out.

Adolescent↗