PubMed Health⌕ Search

Biomedical subjects

M Yaman

Publications and source records attributed to M Yaman.

At least 19 recordsLinked to original sources
PubMed2006

An inventory of the phlebotomine sandflies (Diptera: Psychodidae) found in the Turkish province of Konya.

Between the April and October of 1997, the sandflies in six areas (Centrum, Altinekin, Kadinhani, Cumra, Beysehir and Bozkir) of the Turkish province of Konya, in Central Anatolia, were surveyed. All the sandflies were caught close to houses, on sticky-paper traps placed in barns used by livestock. All 127 specimens of Sergentomyia collected were either S. theodori (86.6%) or S. dentata (13.4%). The other 2017 sandflies caught represented 12 species of Phlebotomus - mostly P. papatasi (78.4%) or P. halepensis (10.9%), with P. sergenti (3.8%), P. simici (2.2%), P. kandelakii (1.6%), P. similis (0.9%), P. jacusieli (0.5%), P. neglectus (0.4%), P. transcaucasicus (0.3%), P. syriacus (0.3%), P. kyreniae (0.3%) and P. balcanicus (0.3%) relatively rare. Most (87%) of the flies were male. This represents the first report of P. transcaucasicus in Turkey. In addition, P. syriacus, P. neglectus, P. similis and S. dentata have not been detected before in Central Anatolia.

Animals↗
PubMed2005

Delayed onset bleomycin-induced pneumonitis.

We describe a 39-year-old male patient who developed bleomycin-induced pneumonitis 2 years after completion of chemotherapy for nonseminomatous testicular cancer. Bleomycin sometimes causes fatal pulmonary toxicity, including bleomycin-induced pneumonitis. The central event in the development of pneumonitis is endothelial damage of the lung vasculature due to bleomycin-induced cytokines and free radicals. Pulmonary toxicity usually begins at bleomycin administration. The development of bleomycin-induced pneumonitis up to 6 months after bleomycin therapy has also been reported. We report a patient who developed bleomycin-induced pneumonitis 2 years after the initiation of bleomycin-containing chemotherapy regimens.

Adult↗
PubMed2004

A case of primary diffuse tracheobronchial amyloidosis.

Tracheobronchial amyloidosis (TBA) is an uncommon localized form of amyloidosis with fewer than 150 reported cases in the literature. We report a case of primary diffuse tracheobronchial amyloidosis who presented with cough, wheezing, recurrent and progressive dyspnea as well as hemoptysis. Though there is no universally accepted treatment for the localized form, this patient was successfully treated with three sessions of bronchoscopic resection and adjuvant steroids. This report will review the various types of amyloidosis of the respiratory tract and their clinical features, in addition to discussing the different available treatment modalities for TBA.

Amyloidosis↗
PubMed2004

The sandflies (Diptera: Psychodidae) in the Turkish province of Hatay: some possible vectors of the parasites causing human cutaneous leishmaniasis.

The province of Hatay, which lies on the Mediterranean coast in south-eastern Turkey, forms an important endemic area for human cutaneous leishmaniasis (HCL). Between the June and November of 2001, the sandflies in eight areas of the province, Erzin, Dortyol, Iskenderun, Kirikhan, Antakya, Samandag, Altinozu and Yayladagi, were surveyed, using sticky-paper traps placed in goat, sheep, cow or chicken sheds close to houses. Although 217 of the 998 sandflies caught belonged to the genus Sergentomyia, the rest were of Phlebotomus species, including some species that, elsewhere, are known to act as vectors of the parasites causing HCL. The Sergentomyia caught were either S. theodori (59.9%) or S. dentata (40.1%). Most of the Phlebotomus were P. sergenti (60.8%) but P. papatasi (18.8%), P. syriacus (9.3%), P. neglectus (5.1%), P. tobbi (2.7%), P. simici (2.2%), P. alexandri (0.9%) and P. kyreniae (0.1%) were also identified (the latter three species for the first time in Hatay province). The identification of the main vector species of sandfly in the province is complicated because it is still uncertain which Leishmania species cause(s) the local HCL. It seems likely, however, that P. sergenti is the main vector in Antakya, Iskenderun, Dortyol, Erzin and Kirikhan. In areas such as Altinozu and Yayladagi, where, although P. sergenti is very rare or absent, HCL cases still occur each year, other species, such as the relatively abundant P. papatasi and P. syriacus, may be the main vectors.

Animals↗
PubMed2003

Comparison of fine-needle aspiration and open biopsy of testis in sperm retrieval and histopathologic diagnosis.

This study aimed to compare the diagnostic value of testicular fine-needle aspiration (FNA) with open biopsy in infertile males with azoospermia or severe oligozoospermia and to evaluate the reliability of testicular sperm extraction by FNA. A total of 76 testes of 40 patients, 34 with azoospermia, four oligozoospermia and two patients who underwent orchidectomy as a result of cancer of prostate were included. Detailed clinical and laboratory examinations were performed and two semen analyses were obtained from each patient. A 20-ml 26 gauge 13-mm needle was used for FNA and smears were stained with May-Grunwald-Giemsa and Papanicolaou stain. An open biopsy was performed in each patient after FNA and the samples were stained with haematoxylen-eosin. Smears and histological stains were examined and compared under light microscopy by the same pathologist. In 69 of the 76 testes (90%) FNA cytology results agreed with the histology. In four testes, the aspirate was unsatisfactory and in three testes, spermatocytic arrest was found cytologically while subsequent biopsies revealed diffuse fibrosis. In 15 of 16 patients (93.7%) with normal and hypospermatogenesis, spermatozoa had been extracted by FNA. Spermatozoa could not be obtained after neither FNA nor open biopsy in the remaining 24 patients. Testicular FNA in infertile males is a simple, reliable and minimally invasive diagnostic tool. It is as effective as open biopsy for testicular sperm extraction and good results can be achieved in experienced hands.

Adult↗
PubMed2002

Sensitization to horse hair, symptoms and lung function in grooms.

OBJECTIVE: This study aimed to investigate the rate of occupational sensitization to horse hair in grooms and whether occupational exposure to horse hair increases respiratory and allergic symptoms and affects lung function in grooms or not. METHODS: This is a cross-sectional study. Two hundred grooms were randomly selected among 1000 grooms working in Veliefendi Hippodrome of Istanbul. One hundred and twenty-five subjects agreed to enter the study. Ninety-two workers who worked in the different parts of this hippodrome enrolled as the control group. A detailed questionnaire including respiratory and allergic symptoms was filled in, physical examination, skin prick tests and pulmonary function tests were performed. RESULTS: Sensitization to horse hair was 12.8% in grooms and 4.3% in controls. The difference was statistically significant (P = 0.0035). Asthma was found in 14.4% of the grooms and 5.4% of the controls, allergic rhinitis in 42.4% of the grooms and 18.4% of the controls, allergic conjunctivitis in 35.2% of the grooms and 15.2% of the controls, and allergic skin diseases in 32.8% of the grooms and 13% of the controls. The differences were statistically significant (P = 0.043, P = 0.0002, P = 0.001 and P = 0.0008, respectively). The means of FEV1, FEV1/FVC and FVC parameters were significantly lower in the groom group (P = 0.006, P = 0.001 and P = 0.003, respectively). In the multivariate analysis, being in the groom group and working years were found to be predictive factors for impairments of lung function (P < 0.001 and P = 0.002, respectively). CONCLUSION: Occupational exposure to horse increases the sensitization to horse hair, induces asthma and allergic symptoms and also impairs lung functions.

Adolescent↗
PubMed2002

Sensitization to sunflower pollen and lung functions in sunflower processing workers.

BACKGROUND: This study aimed to investigate whether exposure to sunflower pollen (Helianthus annuus) increases both sensitization and respiratory symptoms, and whether or not it affects lung functions in sunflower processing workers. METHODS: The largest sunflower processing factories in the Thrace region of Turkey participated in this study. Workers from the units directly exposed to sunflower seed enrolled as the study group (n = 102) and workers who were not directly exposed to Helianthus annuus pollen (n = 102) were the control group. Detailed questionnaires covering respiratory and allergic symptoms were completed, and skin prick tests and lung function tests were performed. RESULTS: We found a very high rate (23.5%) of sensitization to Helianthus annuus in the study group compared to the controls (P<0.001). Logistic regression analysis showed that the risk of sensitization to H. annuus was increased 4.7-fold (odds ratio = 4.17, 95%) confidence interval = 1.3-16.7) if subjects were exposed to sunflower pollen in the workplace. While asthmatic symptoms and allergic skin diseases were not different between the two groups, workers in the study group had a higher rate of allergic rhinitis and conjunctivitis (P<0.05). We found that pulmonary function was significantly impaired in the study group (P<0.01). Using a multivariate analysis model, inclusion in the study group was found to be a predictive factor for impairment of lung function (P=0.002). CONCLUSIONS: We conclude that sunflower pollen has high allergenic potential, especially when there is close contact, and exposure to sunflower pollen in the workplace can result in impairment in lung function.

Agricultural Workers' Diseases↗
PubMed2000

Isolation and insecticidal effects of some bacteria from Euproctis chrysorrhoea L. (Lepidoptera: Lymantriidae).

In this study, we investigated the bacterial pathogens of Euproctis chrysorrhoea and tested for their insecticidal activities. Based on colony color and morphology, four isolates were determined. According to morphological, physiological and biochemical characters of the isolates, they were identified as Enterobacter aerogenes, Lactobacillus sp., Bacillus thuringiensis and Micrococcus luteus. The insecticidal effects of these bacterial isolates on third-fourth instar larvae of Euproctis chrysorrhoea were investigated. The highest insecticidal effect determined on this pest is 68% with Bacillus thuringiensis. The effects of the other isolates are 45% with Enterobacter aerogenes, 15% Micrococcus luteus and 0% with Lactobacillus sp.

Animals↗
PubMed1999

The effect of commencing combination antiretroviral therapy soon after human immunodeficiency virus type 1 infection on viral replication and antiviral immune responses.

Twelve subjects were treated with zidovudine, lamivudine, and ritonavir within 90 days of onset of symptoms of acute infection to determine whether human immunodeficiency virus type 1 (HIV-1) infection could be eradicated from an infected host. In adherent subjects, with or without modifications due to intolerance, viral replication was suppressed during the 24-month treatment period. Durable suppression reduced levels of HIV-1-specific antibodies and cytotoxic T lymphocyte responses in selected subjects. Proviral DNA in mononuclear cells uniformly persisted. The persistence of HIV-1 RNA expression in lymphoid tissues and peripheral blood mononuclear cells suggests that elimination of this residual pool of virus should be achieved before considering adjustments in antiretroviral therapeutic regimens. In addition, given the reduction in levels of virus-specific immune responses, it would seem prudent to consider enhancing these responses using vaccine strategies prior to the withdrawal of antiviral therapy.

Acquired Immunodeficiency Syndrome↗
PubMed1999

Effects of L-thyroxine and zinc therapy on wound healing in hypothyroid rats.

Unfavourable effects of hypothyroidism and zinc deficiency on wound healing are well known. This experimental study was conducted on rats to evaluate the effects of hormone replacement and zinc supplement on wound healing. A total of 50 rats were divided into 5 groups of 10 rats as follows: Control group (A), a hypothyroidism group (B), a L-thyroxine receiving hypothyroidism group (C), a zinc receiving hypothyroidism group (D), and a L-thyroxine plus zinc receiving hypothyroidism group (E). In order to develop hypothyroidism, 5-propyl 2-thiouracil had been given intraperitoneally for a period of 21 days to all groups except the control group. A laparotomy with a 4 cm median incision was performed in all rats. The first half of the rats was sacrificed on the 7th day and the remaining on the 14th day. Breaking strength, hydroxyproline concentrations in the healing scar tissue and blood serum zinc levels were measured. Although both values--breaking strength and hydroxyproline levels--, compared to all others, were found to be higher in the L-thyroxine plus zinc receiving group (group E) on the 7th day, differences among the groups were not statistically significant. However, on the 14th day, these differences were found to be significant. We conclude that the hormone replacement therapy in hypothyroidism cases was beneficial with regard to wound healing and the results were more satisfactory if zinc was added to the therapy.

Animals↗
PubMed1998

Subependymal giant-cell astrocytoma associated with tuberous sclerosis: case report.

Tuberous sclerosis is a neurocutaneous syndrome with a wide variety of clinical, pathologic, and radiologic manifestations. Intracranial phakomatosis has been reported to include subependymal nodules; cortical tubers, and subependymal giant-cell astrocytomas. Subependymal giant-cell astrocytomas are rare, benign brain tumors of unknown histogenesis which cause increased intracranial pressure, seizures, and focal neurologic signs. The only treatment of these tumors is total surgical removal, because they are not sensitive to irradiation and chemotherapy. We report a patient with tuberous sclerosis who underwent surgery for a large subependymal giant-cell astrocytoma.

Angiofibroma↗
PubMed1995

Chronic relapsing pancreatitis from a scorpion sting in Trinidad.

Chronic relapsing pancreatitis is a rare cause of abdominal pain in children and exceptionally rarely is related to a scorpion sting. We describe a 13-year-old girl who, following envenoming by a scorpion, developed recurrent attacks of sharp, intermittent pain in the umbilical region associated with fever, nausea, anorexia and vomiting, and changes in her psychological behaviour. Thorough clinical evaluation, including CT scanning, disclosed unabated pancreatitis. A modified Puestow procedure was performed with very good results. Physicians should be aware that in chronic relapsing pancreatitis, particularly in children, a scorpion sting should be considered an aetiological possibility.

Abdominal Pain↗